Wednesday, May 22, 2013

USA Postdoctoral Position to study: Innate T cells in Inflammation and Infection

Our laboratory in the Department of Pathology at Brigham and Women’s Hospital and Harvard Medical School in Boston, MA, studies the immunobiology of innate T cells. We are particularly interested in the mechanisms that activate CD1d-restricted Natural Killer T (NKT) cells and their role and function during inflammation and microbial infection. Current projects in the lab are focused on understanding the recognition of CD1d-presented microbial and self-lipid antigens and the regulation of their expression, the mechanisms of activation of NKT cells, and the function of NKT cells during inflammation and infection. We are studying both invariant (type I) and diverse (type II) NKT cells using cutting edge molecular biology, cellular immunology, and lipid chemistry techniques, as well as genetically modified in vivo mouse models, and collaborate extensively with local, national and international research groups. For more information on the Brigl lab, please visit: http://brigl.bwh.harvard.edu/.
This position provides an opportunity to build a highly novel set of skills and expertise using cutting edge technologies, and to work in a highly dynamic research environment. The lab and department are in close proximity to the rich and innovative research environment within the Harvard and wider Boston research communities.
The successful applicant is highly self-motivated, able to work independently and in collaborative relationships within the lab and with our outside collaborators. Applicants must have a Ph.D. or M.D. degree that was awarded within the last three years in the area of immunology, and experience working with mouse models. Stipends will be in accordance with NIH and institutional guidelines.
To apply: If you are interested, please submit a CV; a brief description of your background, research accomplishments, interests, and career goals; contact information (email address and phone number) of three references who are familiar with your work; and pdfs of any relevant publications to: mbrigl@rics.bwh.harvard.edu.

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