In particular, we are studying the
biology of refractory leukemias and pediatric renal tumors, and we are
interested in understanding the principles of dysorganization of their
genomes and proteomes, and determining the molecular mechanisms of
response and adaptation of tumor cells to targeted therapies.
To answer these questions, we are
developing new approaches, based on functional genomics and mass
spectrometry proteomics, to decipher the mechanisms of genomic
plasticity and adaptive signaling.
This post-doctoral research position
will leverage an integrated team of researchers using functional
genomics and proteomics, dedicated multi-dimensional nanoscale liquid
chromatographs and high-resolution mass spectrometers, and dynamic
intellectual environment of the SKI. Please see our website for full
details of the research project.
Requirements:
An ideal candidate is a PhD graduate
with experience in mass spectrometry and analytical chemistry, who is
interested in developing a research programme in functional cancer
proteomics. Hands-on experience with the operation of high-resolution
mass spectrometers and nanoscale chromatographs, and design of
experiments using quantitative proteomics are essential.