Postdoctoral research associate position - cellular biophysics/ developmental biology 2013 - United States

POSTDOCTORAL RESEARCH ASSOCIATE POSITION

The Laboratory for Tissue Engineering and Morphogenesis ( http://www.rpi.edu/~wanq ) in the Department of Biomedical Engineering at Rensselaer Polytechnic Institute invites applications for a Postdoctoral Research Associate position in the research areas of Cellular Biophysics and Engineering. This position is open immediately until filled.

We seek highly motivated individuals who enjoy working in a team while concomitantly desiring to pursue their own ideas in a very supportive environment. Our lab combines micro-/nano- technology, molecular and cellular biology, cell biomechanics, and imaging techniques to better understand the biophysics of tissue morphogenesis in development. Specifically, this position is focused on understanding a newly discovered property of cells, cell chirality (also known as cellular left-right asymmetry) and exploring its application in developmental biology and drug screening.

Candidates must possess an earned Ph.D. or a foreign degree equivalent in a relevant area at the time of appointment. Research training in cellular biophysics and developmental biology is highly desired.


We offer an excellent benefits package including health, dental, life insurance, retirement, tuition, etc. Please visit our Human Resources website at: http://hr.rpi.edu.

To apply
Application materials accepted until positions are filled. Interested individuals should send a CV with contact information of three references to wanq@rpi.edu or the address below:

Rensselaer Polytechnic Institute
Professor Leo Q. Wan: Postdoctoral Research Associate Opening
Biomedical Engineering Department
110 8th Street, Troy, NY 12180-3590

We welcome applications from candidates who will bring diverse cultural, ethnic, and national and international perspectives to Rensselaer’s work and campus communities.

Rensselaer is an Equal Opportunity/Affirmative Action Employer.
Department Website

Postdoc position Microbiology/ Biochemistry 2013, Germany

Research of structure, function, biosynthesis and host interaction of bacterial cell envelope components word wide has attracted more and more interest in the recent years. Members of the SFB 766 have contributed to this development: The SFB 766 has already generated a strong international reputation in it`s first 4 year funding period.

In the second funding period we have one open positions for two years for a

PhD student or postdoc (E13, 65%) with the topic

"The bacterial cell envelope as a target structure for dermcidin"

PhD students or postdocs will work on a challenging project at the frontier of the current research. The research group is located at the University Hospital, Department of Dermatology.

The candidate should have a completed diploma / master degree in Microbiology, Biochemistry or related disciplines and a strong background and interest in genetic,biochemical or biophysical methods and microbiological procedures.

The University of Tübinges strives to increase the percentage of female researchers and is explicitly urging scientifically qualified women to apply. Disabled scientists with equal qualification will be hired preferentially.

Please send your full application to:
Prof. Dr. rer. nat. Birgit Schittek, University of Tübingen, Department of Dermatology, Lieberemeisterstr. 25, 72076 Tübingen or per email to birgit.schittek@med.uni-tuebingen.de
Application deadline: July 31th, 2013

For further information please contact Prof. Dr. Birgit Schittek (see email adress above).

Postdoctoral Researcher position at Institute of Biomedicine, Finland

An appointee to the position of post-doctoral researcher shall hold a doctoral degree, have the ability to conduct independent scholarly work and have the teaching skills necessary for the position. Experience in molecular biology, protein chemistry, biochemistry or biophysics is required.

The goal of the new laboratory at the Institute of Biomedicine is to develop novel fluorescent proteins, genetically-encoded biosensors and optogenetic tools as well as advanced microscopy methods to be employed for analysis, manipulation and modification of biochemical processes in live cells and model animals using light.

http://www.helsinki.fi/recruitment/index.html?id=69614

Postdoctoral researcher in the Department of Physiology and Biophysics, United States

There is an immediate opening for a postdoctoral researcher in the Department of Physiology and Biophysics, Universityof Californiaat Irvine. The candidate is expected to carry out mass spectrometry-based proteomic and biochemical approaches to study interactions, structures and posttranslational modifications of protein complexes in the ubiquitin-proteasome system and thus understand the function and regulation of protein complexes during cancer development. The lab is equipped with a LTQ-Orbitrap mass spectrometer (Thermofisher) and several HPLC systems for protein and peptide analysis.  Ph.D. degree in biochemistry, molecular biology, chemistry or related fields is required, and experience in protein expression and purification is preferred. Skills and knowledge in molecular and cell biology, and/or protein and peptide separation will be a plus. The ideal candidate should be a highly motivated individual with a strong record of research accomplishments.  Please email your current CV with the list of publications and the contact info of three referees to Prof. Lan Huang (lanhuang@uci.edu).                      

The University of California, Irvine is an equal opportunity employer committed to excellence through diversity.

Postdoctoral position to study Prion - 2013 USA

Postdoctoral position is available in Center for Biomedical Engineering and Technology (BioMET) and Department of Anatomy and Neurobiology at University of Maryland School of Medicine, Baltimore, USA. Our laboratory focuses on elucidation of mammalian prion replication mechanism. Ongoing studies include biochemical, molecular imaging, structural, cellular, neuropathological and experimental animal approaches to understand the mechanisms by which prions replicate, to elucidate molecular structure and define molecular features responsible for prion infectivity and prion strain diversity.  

This position is intended for a highly motivated individual with new or recent PhD in biochemistry, biophysics, structural biology, neuroscience, cell and molecular biology or related fields. Candidates with experience in one of the following areas are preferred: prions, membrane and lipid biology. Candidates are expected to have analytical skills and be proficient in oral and written communication. 

To apply

Send a curriculum vitae, a letter stating research interest and contact information for three references to Dr. Ilia Baskakov, Associate professor, Email: Baskakov@umaryland.edu

http://www.umaryland.edu

Biophysics/ Biophotonics/ Bioengineering Postdoctoral position 2013 - China

    The Laboratory of Biophysics and Quantitative Biology (http://www.phy.cuhk.edu.hk/people/wu.html) at the Department of Physics of the Chinese University of Hong Kong is seeking a Postdoctoral Researcher in experimental biophysics/biophotonics.  We are studying a range of fundamental questions on bacterial life in communities (biofilms), with a focus on cell-environment interactions.

    Candidates should have strong experimental skills and publication record in (bio) physics, (bio) photonics, bioengineering, or soft matter physics.  Experience in biochemistry or molecular biology is preferred.  Candidates should be highly motivated for working in an interdisciplinary environment and enthusiastic about pursuing the physics of living systems.  Excellent communication and language skills are required.

    The employment contract is initially for one year and renewable annually, subject to mutual satisfaction.  The position is available until filled.

    Please send applications including a cover letter and a CV with names of three references to Prof. WU Yilin  at <ylwu@phy.cuhk.edu.hk>.

• Website: http://www.cuhk.edu.hk/english/aboutus/university-intro.html
• Dept Site: http://www.phy.cuhk.edu.hk/people/wu.html

Cell/ developmental biology/ Biophysics - Postdoctoral position 2013 at Denmark

The Novo Nordisk Foundation Section for Basic Stem Cell Biology (BasicStem) at DanStem and the Faculty of Health and Medical Sciences, University of Copenhagen, has been established to promote basic and applied research on stem cell- and developmental biology of medical relevance. The Center comprises a wide range of expertise and skills, from embryological model systems, mouse genetics, stem cell studies, and in vitro culture systems to stem cell therapeutics. Currently, we have recruited >40 staff members to our research groups and staff functions, and expect to expand to around 60 scientists in the future.
Job Description:

We are recruiting an outstanding, ambitious postdoctoral candidate with a strong background in interdisciplinary cell/developmental biology and biophysics to join our group. The postdoctoral candidate will study how mechanotransduction via cell-cell interactions and cytoskeletal dynamics controls pancreatic morphogenesis and cell fate specification. The primary focus in this project will be to develop and analyse novel time lapse imaging models for simultaneous tracking of changes in cell shape, migration, polarity and fate. Towards this goal a combination of unique fluorescent reporter mouse strains will be inter-crossed with various mouse models with conditional gene inactivation of key morphogenetic regulators (including Rho GTPases and downstream components) in the developing mouse pancreatic epithelium. The candidate should have previous experience with confocal microscopy on an advanced level, and ideally also experience with live imaging of cells/organs using fluorescent reporters. Furthermore, experience in mouse genetics, fine dissection, Imaris and/or Fiji software, and script writing is considered of particular relevance.
Qualifications:

•     A PhD in cell biology, genetics, developmental biology, biophysics or a similar field;
•     An excellent publication record along with experience in developmental biology/biophysics is essential;
•     Advanced training and experience (>3 years) in confocal microscopy is essential;
•     Experience in live imaging as well as 3D and movie processing in Imaris/Fiji or similar software is ideal;
•     Experience with the mouse as an experimental model and mouse genetics is ideal;
•     Strong motivation and excellent scientific skills are essential;
•     Good English communication skills, both oral and written;
•     An analytical aptitude of devising innovative scientific or technical solutions;
•     Demonstrate enthusiasm, motivation, flexibility and confidence.

Application Instruction

The application must be submitted in English, by clicking on?
The closing date for applications is 23.59pm, 30th April 2013.

More Information

Industrial Postdoctoral Position for biochemist/ biophysicist/ crystallographer at AstraZeneca, USA

We have an exciting opportunity for a biochemist/biophysicist/crystallographer to join the Structure & Biophysics group at AstraZeneca in Waltham, MA. This is a collaborative effort with the laboratory of Professor Jamie Cate at the University of California Berkeley to understand the structural basis of mechanism-based toxicity to antibiotic treatment. Success in generating chimeric ribosomes will result in novel means to assess antibacterial sensitivity using a suite of genetic, biochemical and biophysical approaches.

This position provides an opportunity to explore the gene-to-structure process in an industrial setting. You'll be exposed to a variety of aspects within the drug discovery cascade, and will interact with scientists in a cross-disciplinary environment. You'll also be expected to deliver your novel research results within AstraZeneca, and externally via scientific conferences and peer-reviewed publications.

Your major responsibilities


* Build an understanding of antibiotic selectivity for the bacterial ribosome through the design and analysis of the functional activity of chimeric ribosomes
* Assess the antibacterial sensitivity of recombinant bacterial strains containing chimeric ribosomes against a panel of known ribosomal inhibitors
* Understand the structural basis of ribosomal inhibitor selectivity by performing crystallography on chimeric ribosomes in complex with antibiotics
* Work collaboratively with scientists across various disciplines to achieve project objectives
* Externally present results at scientific conferences, and publish scientific papers in high quality peer-reviewed journals


Minimum experience

A PhD in one or more of the following areas:


* Protein/RNA biochemistry
* Biophysics, crystallography, ribosome biology, molecular microbiology


Preferred experience/requirements


* Molecular biology, expression and purification skills to independently produce high-quality RNA-protein complexes
* Experience with multiple biochemical and biophysical techniques to assess the quality, stability and function of RNA-protein complexes
* Experience in performing antibacterial sensitivity assays
* Experience in designing complex reagents for biophysical and crystallographic studies
* Crystallographic experience is highly desirable
* Strong written and oral communication skills

Apply Now

Postdoctoral Position in Biophysics 2013 - USA

Three-dimensional cell culture models have emerged as effective systems to study tissue differentiation and cancer behavior. If cancer is fundamentally a disease of aberrant multicellular organization, then understanding the effects of the tissue microenvironment (e.g., engineered matrices), cellular and molecular variables, and possible therapeutic interventions on the oncogenic phenotype requires the development and use of more sophisticated models that can approximate cell-cell and cell-matrix interactions in vivo.

Position requires designing innovative experiments for identifying stress responses in co-cultured multicellular systems, validating markers, and designing prognostic assays. This is an exciting position where applicant will be conducting research with a multidisciplinary team of molecular and computational biologists. Applicant will be supported by a strong team computational and informatics staff for quantifying dynamics of multicellular organization.
There is a tremendous amount of growth for innovation and career development.

Responsibilities:
* Design innovative experiments for characterizing stress responses in multicellular systems
* Establish a pipeline for high throughput imaging of multicellular system
* Skilled in molecular biology and cloning strategies
* Publish research materials in leading journals
* Maintain a clear record of research progress and data collected, and Assist PI in developing reports and new proposals



Requirements:
* Ph.D. or equivalent experience in molecular biology, cell biology, and protein biochemistry techniques as evidenced by publications
* Skilled in 3D cell cultured models and engineered matrices
* Applicant must be an expert in fluorescent microscopy, live cell imaging, sample preparation, and maintain the required safety records.
* Skilled in RNA collection
* Excellent communication skills with ability to follow verbal and written instructions and ability to organize and document research results accurately
* Ability to prioritize assignments and meet deadlines
* Knowledge of working for plants and microorganisms is desirable.
This is a 1-year, term appointment with the possibility of renewal for up to 5 years based upon satisfactory job performance, continuing availability of funds, and ongoing operational needs.

How to Apply:
For full consideration, follow the link to the job posting and apply directly to Berkeley Lab. As part of the online application process, please complete a profile, including uploading attachments relevant to the opportunity.

For More Information

Post-doctoral Scientist position 2013 at The MRC Laboratory of Molecular Biology

Post-doctoral Scientist – 3 Year Fixed Term
Starting Salary £26,282 to £28,083 per annum
Band Salary £26,282 to £37,040per annum

Currently in our Centenary year, The MRC Laboratory of Molecular Biology (LMB) is one of the birthplaces of modern molecular biology and has played an important role in the development of many new techniques, most notably X-ray crystallography of proteins, DNA sequencing and monoclonal antibodies.

With the opening of our new laboratory the LMB provides an unsurpassed environment for both young and established researchers. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation.

The purpose of the role will be to work within a programme aimed at studying AMPA receptor signalling in neuronal cultures and slices. Specifically, to investigate AMPAR subunit remodelling and dendritic targeting in hippocampus in response to altered neuronal activity and the role of RNA editing therein. In addition to brain slice electrophysiology this project involves confocal microscopy and transgenic mice. For more information please contact I Greger (ig@mrc-lmb.cam.ac.uk), and Penn and Greger (2009), RNA Biol; Penn et al Neuron (2012); Balik et al Nucleic Acids Res (2013).c

Candidates should have a PhD in a biological or biophysical subject and good experience with electrophysiological recordings. Experience with brain-slice recordings would be advantageous. A basic knowledge of standard molecular biology techniques or confocal microscopy would be desirable. For more information please contact Dr. I. Greger: ig@mrc-lmb.cam.ac.uk

Successful applicants will be awarded a three-year Career Development Fellowship. The fellowship is a training and development position for a post-doctoral scientist who has recently completed their doctoral studies, and is moving into a new research discipline.

Your salary will be supported by 30 days annual leave entitlement, an optional MRC final salary pension scheme and excellent on-site sports and social facilities.

Applications are handled by the RCUK Shared Services Centre; to apply please visit our job board at http://www.topcareer.jobs/Vacancy/irc89370_2935.aspx and submit your CV along with a Cover Letter quoting the IRC number. If you are unable to apply online please contact us on 01793 867003 quoting reference IRC89370.

Closing date: 5 May 2013

Final appointments will be subject to a pre employment screening
The Medical Research Council is an Equal Opportunities Employer"

Postdoctoral Fellow Next Generation Detector for Protein Crystallography 2013 - Switzerland

The Paul Scherrer Institute, PSI, is with 1500 employees the largest research centre for natural and engineering sciences within Switzerland. We perform world-class research in three main subject areas: Matter and Material; Energy and the Environment; and Human Health. By conducting fundamental and applied research, we work on long-term solutions for major challenges facing society, industry and science.

The Swiss Light Source (SLS) is one of the most advanced radiation sources worldwide. The SLS Macromolecular Crystallography Group operates two high performance undulator beam lines as well as a state-of-the-art bending magnet beamline for protein crystallography. The group is involved in several aspects of protein crystallography including the development of advanced beamline instrumentation and crystallographic methods, as well as structural biology projects in collaboration with the Biomolecular Research Group at PSI and external partners.

We are looking for a

Postdoctoral Fellow

Next Generation Detector for Protein Crystallography

Your tasks

Built on the success of PILATUS detector technology, PSI and Dectris Ltd. are developing the next generation single-photon counting detector (EIGER) featuring smaller pixel size, higher frame rate and dynamic range. The proposed project is to exploit PILATUS and EIGER detectors in protein crystallography applications:

• Systematic data acquisition and processing optimization using PILATUS 2M/6M detectors
• Development of fast data acquisition and processing methods with EIGER 1M detector in protein micro-crystallography
• Commissioning of the EIGER 16M detector at a protein crystallography beamline

Your profile

You hold a PhD degree in (bio-) chemistry or physics and have several years of experience in protein crystallography. Working knowledge for data processing programs and various phasing and refinement software is a must. Experience in computer programming would be a significant advantage. If you are a good team player with fine communication skills and sense of responsibility, this position will offer a great opportunity for you to develop your research career in an exciting and highly multidisciplinary environment.

For further information please contact Dr Meitian Wang, phone +41 56 310 41 75 or Dr Clemens Schulze-Briese, phone +41 56 500 21 20.

Please submit your application online (including list of publications and addresses of referees) for the position as a Postdoctoral Fellow (index no. 6112-00).

Paul Scherrer Institute, Human Resources Management, Elke Baumann, 5232 Villigen PSI, Switzerland

http://www.psi.ch/pa/offenestellen/

Apply Now 

UK: Post-doctoral position at The MRC Laboratory of Molecular Biology - April 2013

"Currently in our Centenary year, The MRC Laboratory of Molecular Biology (LMB) is one of the birthplaces of modern molecular biology and has played an important role in the development of many new techniques, most notably X-ray crystallography of proteins, DNA sequencing and monoclonal antibodies.

With the opening of our new laboratory the LMB provides an unsurpassed environment for both young and established researchers. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation.

The purpose of the role will be to work within a programme aimed at studying AMPA receptor signalling in neuronal cultures and slices. Specifically, to investigate AMPAR subunit remodelling and dendritic targeting in hippocampus in response to altered neuronal activity and the role of RNA editing therein. In addition to brain slice electrophysiology this project involves confocal microscopy and transgenic mice. For more information please contact I Greger (ig@mrc-lmb.cam.ac.uk), and Penn and Greger (2009), RNA Biol; Penn et al Neuron (2012); Balik et al Nucleic Acids Res (2013).

Candidates should have a PhD in a biological or biophysical subject and good experience with electrophysiological recordings. Experience with brain-slice recordings would be advantageous. A basic knowledge of standard molecular biology techniques or confocal microscopy would be desirable. For more information please contact Dr. I. Greger: ig@mrc-lmb.cam.ac.uk

Successful applicants will be awarded a three-year Career Development Fellowship. The fellowship is a training and development position for a post-doctoral scientist who has recently completed their doctoral studies, and is moving into a new research discipline.

Your salary will be supported by 30 days annual leave entitlement, an optional MRC final salary pension scheme and excellent on-site sports and social facilities.

Applications are handled by the RCUK Shared Services Centre; to apply please visit our job board at http://www.topcareer.jobs/Vacancy/irc89370_2935.aspx and submit your CV along with a Cover Letter quoting the IRC number. If you are unable to apply online please contact us on 01793 867003 quoting reference IRC89370."


Closing date:     2013-04-21


http://www.topcareer.jobs/Vacancy/irc89370_2935.aspx

UK : Post-doctoral Scientist position in biophysical chemistry at MRC Laboratory of Molecular Biology

Post-doctoral Scientist – 3 Year Fixed Term
Starting Salary £26,282 to £28,083 per annum
Band Salary £26,282 to £37,040per annum

Currently in our Centenary year, The MRC Laboratory of Molecular Biology (LMB) is one of the birthplaces of modern molecular biology and has played an important role in the development of many new techniques, most notably X-ray crystallography of proteins, DNA sequencing and monoclonal antibodies.

With the opening of our new laboratory the LMB provides an unsurpassed environment for both young and established researchers. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation.

The purpose of the role will be to work within a programme aimed at studying AMPA receptor signalling in neuronal cultures and slices. Specifically, to investigate AMPAR subunit remodelling and dendritic targeting in hippocampus in response to altered neuronal activity and the role of RNA editing therein. In addition to brain slice electrophysiology this project involves confocal microscopy and transgenic mice. For more information please contact I Greger
(ig@mrc-lmb.cam.ac.uk), and Penn and Greger (2009), RNA Biol; Penn et al Neuron (2012); Balik et al Nucleic Acids Res (2013).

Candidates should have a PhD in a biological or biophysical subject and good experience with electrophysiological recordings. Experience with brain-slice recordings would be advantageous. A basic knowledge of standard molecular biology techniques or confocal microscopy would be desirable. For more information please contact Dr. I. Greger:
ig@mrc-lmb.cam.ac.uk

Successful applicants will be awarded a three-year Career Development Fellowship. The fellowship is a training and development position for a post-doctoral scientist who has recently completed their doctoral studies, and is moving into a new research discipline.

Your salary will be supported by 30 days annual leave entitlement, an opt"

Contact Information
Miss Emma Williams
RCUK
Shared Service Centre
North Star Avenue
SN2 1FF Swindon
Wiltshire
Phone:    
Fax:    
E-mail:    
Website:     http://www.topcareer.jobs/Vacancy/irc89370_2935.aspx

Closing date:     2013-04-21