Monday, October 21, 2013
- Flow cytometry
- Immunofluorescence staining
- Confocal microscopy
- Molecular cloning
- RRT-PCR
- Cell culture
- Standard microbiological techniques
- Animal handling skills
Friday, October 18, 2013
Thursday, October 17, 2013
Wednesday, October 16, 2013
Application should include a letter of motivation, a CV and a short summary of your current researches and center of scientific interest.
The candidate will study the role of inducible Bronchus Associated Lymphoid tissue (iBALT) in immunity to tuberculosis (see Slight et al, Journal of Clinical Investigation, 2013; Gopal et al, Mucosal Immunology, 2013). The successful candidate should have a recent Ph.D. in Microbiology/ /Immunology/Molecular Biology (within the past year), peer-reviewed publications, be highly motivated and fluent in English. Prior experience with flow cytometry, immunofluorescence staining, confocal microscopy, molecular cloning, cell culture, standard microbiological techniques and animal handling skills are required. BSL-3 training is desirable. To apply: Please send curriculum vitae, a brief research statement describing future goals, and the names of three references via e-mail in a single PDF to khader@borcim.wustl.edu.
Friday, July 5, 2013
Starting Date: from 1st November 2013 on
Duration: 18 months
Funding: German Federal Ministry of Education and Research (Program: "Next Generation Biotechnology - Biotechnologie 2020+")
In the frame of the transdisciplinary project "Biomolecular Interaction Engineering" funded by the German Federal Ministry of Education and Research, the newly created group of Dr Guillaume Delaittre is seeking a highly motivated postdoctoral researcher to engineer proteins, particularly enzymes, in order to incorporate them into biohybrid nanostructured materials. Molecular biology protocols as well as direct chemical modifications are envisaged in order to stabilize the biomolecules and equip them with a wider range of surface chemical functionality, while maintaining their biological activity.
Interaction with a broad range of biologists, chemists, physicists, and engineers will be facilitated by the physical and scientific embedding of the research team at the transdisciplinary Institute of Toxicology and Genetics. Collaboration with the internationally renowned Polymer and Materials Chemistry team of Prof. Barner-Kowollik will be promoted through our joint weekly group seminar. Importantly, the KIT is a multidisciplinary research institute offering access to nearly all scientific equipment one can think of.
The applicants must have completed a PhD degree in Biology (or Chemistry). Prior hands-on experience with protein modification is a strict requirement. A successful candidate is mandatorily well-versed in modern protein biochemistry and characterization, e.g., gel electrophoresis, mass spectrometry, liquid (affinity or size-exclusion) chromatographies, UV and fluorescence spectroscopies, enzyme and antibody assays, light scattering. Ideal applicants also possess knowledge in enzyme kinetics. Although it is not a strict requirement, applicants who are familiar (at least theoretically) with analytical methods such as NMR, electron microscopy, and surface characterization techniques and have a background in organic and polymer chemistry will be in a good position. Some interest in materials-related research is welcome. A good level of English is essential.
Read Further
Successful candidate should be highly motivated and has a recent PhD in molecular biology and neuroscience. Strong background and hand-on experiences in molecular cloning, viral work, animal surgery, and confocal imaging are desirable. Strong communication and organization skills are required.
Interested candidates should send CV, a brief statement of research accomplishments and interests, any published papers, as well as names and contact information of 3 references to xli4@lsuhsc.edu or keigen@lsuhsc.edu. LSUHSC-NO is an EO/AA employer
Application Deadline: 9/30/2013
Thursday, July 4, 2013
For recent project-relevant publications of our group, see:
Original Article: Thunemann, Wen et al. (2013). Transgenic mice for cGMP imaging. Circ Res, in press.
Methods Article: Thunemann et al. (2013). Visualization of cGMP with cGi biosensors. Methods Mol Biol 1020, 89-120.
Review Article: Kemp-Harper & Feil (2008). Meeting report: cGMP matters. Sci Signal 1, pe12.
For further information, please visit www.cyclic-gmp.de or www.ifib.uni-tuebingen.de/forschung/feil.html.
Please send your application (including names/emails of 2 referees) to Prof. Dr. Robert Feil, University of Tübingen, Interfakultäres Insitut für Biochemie (robert.feil@uni-tuebingen.de).
Deadline for applications: 16 August 2013
The J. Craig Venter Institute (“JCVI”), a not-for-profit research institute dedicated to the advancement of the science of genomics is seeking a Post-Doctoral Fellow to join Dr. David Wentworth’s team in the Virology Group at our Rockville, MD location. The major responsibilities of this position will include influenza virus genomics/phylogeny and the development of methods to amplify and analyze the genome of BSL3/4 viral pathogens. Other responsibilities will include designing and executing experiments, analysis of experimental results/data, and training other team members. As a member of a scientific team Post-Doctoral Fellows are also expected to help develop new scientific projects by assisting with the preparation of proposals and to publish the results of their work in peer-reviewed journals.
Qualified candidates will possess a Ph.D. in virology and experience with influenza viruses, and molecular virology including reverse genetics approaches. Preference will be given to candidates that have experience influenza virus replication, pathogenesis and/or vaccine development.
JCVI offers an excellent working environment and a competitive benefits package. For more information and to apply to this position, please visit our website at www.jcvi.org Equal Opportunity Employer M/F/D/V.
To apply
For more information, please visit our web site at www.jcvi.org. Reference Code: INFE992
Department Website
The mucus barrier, antimicrobial proteins and IgA operate together to confine symbiotic bacteria towards the outer mucus layer and protect the epithelial surface by limiting bacterial penetration. This homeostatic interaction between mucus and gut commensals is critical to maintain gut health. Intestinal pathogens have evolved strategies for subverting and evading these barriers to access host tissues. By contrast, there is currently very limited knowledge of the mechanisms resident members of the intestinal microbiota interact with components of the mucus barrier.
Mucus-binding proteins (MUBs) are a class of cell-surface adhesins found in Gram-positive gut symbionts, shown to mediate interaction of bacteria to mucus. Building on our extensive preliminary data on the structural and biochemical properties of MUB, the purpose of this study is to determine the molecular and cellular basis of MUB interactions with receptors of the mucus layer, mucins glycans and mucosal antibodies and assess the potential of the impact of MUBs and IgA interaction on bacteria adhesion to mucus and IgA effector function, providing mechanistic insights into the regulation of gut microbiota homeostasis. Understanding the molecular basis of these processes will help understand how some bacteria strains exert intestinal health protection and devise intervention strategies to reinforce gut health.
This interdisciplinary project will benefit from the established international network of collaborations of the Lab in this area of research. In addition to the proposed experimental work, the post-holder will contribute to the research by interacting with research scientists and PhD students in the Group and by following up existing collaborations with scientists on the Norwich Research Park and with external collaborators, writing-up reports and publications, presenting at relevant meetings and Conferences. The post-holder will be encouraged to present his/her results to the general public by joining IFR-led Public Engagement activities. In addition, he/she will benefit from regular BBRSC-sponsored training courses in career development and transferable skills.
Key relationships
The post-holder will work in the Gut Health and Food Safety Programme and will be line-managed by Dr Nathalie Juge. He/she will work closely with PhD students and with research assistants , Louise Tailford and Donald MacKenzie in the Juge Group. The successful candidate will be expected to present work at internal Lab Programme and meetings and at Conferences.
Main Activities & Responsibilities
- MUB ligand characterisation in vitro and binding kinetics & thermodynamics
- Lactobacillus reuteri binding specificity to cell lines and in vitro tissue culture models
- MUB binding specificity to cell lines and host tissues
- MUB and MUB repeat purification and characterisation
- Writing-up reports, publications, presentations
- Contribute to Lab supervision
Education & Qualifications
- PhD biochemistry/molecular microbiology/cell biology or equivalent experience
- BSc in Biological Sciences
- Expertise in glycobiology
- Expertise in gut microbiology
Read Further about the position
Wednesday, July 3, 2013
Postdoctoral research position available immediately for highly motivated candidate to help develop gene expression approaches for biological dosimetry, and to study the effects of different radiation modalities (dose, dose-rate, LET, organ-specific effects).
The laboratory is part of the Center for Radiological Research (http://crr-cu.org/) in the Department of Radiation Oncology at Columbia University. Some of the research will involve use of our Radiation Research Accelerator Facility (http://www.raraf.org/) located just outside New York City in Westchester County.
Successful candidates must have experience in cellular and molecular biology, especially RNA work, as well as excellent communication skills, and a high level of proficiency in one or more of the following areas: radiation biology, microarray and bioinformatics, mouse work, biodosimetry.
Please be sure to include a statement of research interests, CV with publication list, and contact information for three references with application.
Columbia University Medical Center is an Affirmative Action / Equal Opportunity employer.
To apply click here
Applicants must be experienced researchers with a doctoral degree related to medical/biological sciences and interest in cardiovascular diseases. Applicants must possess a strong publication record, with experience in molecular biology, cell biology and signaling. Experience with animal models of regeneration and hematopoietic/cardiac stem cells is preferable.
We offer a 2 year contract with competitive salary according to the experience of the selected candidate. The CNIC has an advanced policy on matters of welfare benefits, with the most modern flexible remuneration systems.
To apply
Qualified applicants should submit an application by e-mail, including a letter outlining research interests, a CV, and the contact information of three referees, to Eduardo Bieger (ebieger@cnic.es)
http://www.cnic.es/en/inflamacion/metaloproteinasas/index.php
Tuesday, July 2, 2013
at the 3rd Medical Deparmtment of Hematology and Oncology (Director: Univ.-Prof. Dr. Christian Peschel) at Klinikum rechts der Isar (Technische Universität München) is offering a position for a
Postdoctoral fellow
Our research group studies the interplay between innate and adaptive immunity in infectious
and malignant diseases and is situated in a highly stimulating research environment. Our
research is supported by the German research foundation and the Else-Kröner-Research-Foundation.
Applicants should have a MD or PhD or equivalent doctoral degree with at least 3 years of
proven research experience in Immunology, Cell / Molecular Biology or Biochemistry. Prior
experience with in vivo technologies will be of advantage. The ideal candidate should be a
highly motivated and goal-oriented researcher, provide a good publication record, be able to
work in a team as well as show some experience in the supervision of graduate students or
master students.
Payment is according to tarif (TV-L). We give priority to severely disabled applicants with essentially equal qualifications.
Please submit your complete application documents (including CV, motivation letter,
publication list and references - all documents within a single PDF file) via E-mail to:
PD Dr. med. Hendrik Poeck or Dr. med. Tobias Haas
III. Medizinische Klinik und Poliklinik
Klinikum rechts der Isar
der Technischen Universität München
Ismaninger Straße 22 ∙ 81675 München
Email: hendrik.poeck@lrz.tum.de or tobias.haas@lrz.tu-muenchen.de
Website:
http://www.med3.med.tu-muenchen.de/forschung/Grundlagenforschung/Tumorimmunologie/haaspoeck.html
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