Germany: Postdoctoral Scientist position in Bioinformatics/ Computational Biology/ Plant Genomics

The Max Planck Institute for Molecular Genetics is an international research institute with approximately
350 employees. A special focus lies on genome analysis of man and other organisms.

The Department “Vertebrate Genomics”, group “Comparative and Functional Genomics” (Head: Dr. Heinz Himmelbauer), invites applications for the following open position:

Postdoctoral Scientist (f/m)

Bioinformatics/Computational Biology/Plant Genomics

(TVöD E13)

Code: 13-12 L

Responsibilities:
The AnnoBeet project is funded by the German Ministry for Education and Research with the goal to analyse the genome sequence of the crop plant sugar beet (Beta vulgaris) with respect to structural variation and gene functions. The successful candidate will pursue projects related to genomic sequencing data. She/He will adapt existing tools or implement new software to assemble high-fidelity genome sequences from wild-derived and domesticated beets. Data are mainly from the Illumina sequencing platform but also from other technologies which enable the generation of long reads. Assembled genomes will be compared to related genomes to extract and interpret biologically relevant differences.

Qualifications:
We are looking for a scientist (PhD in bioinformatics or related field) with solid programming skills (ideally experience in developing sequence analysis tools), experience in handling (large) sequencing data sets, knowledge of molecular genetics and understanding of lab methods and also knowledge of genome sequencing concepts. Experience in analysis of Illumina sequencing data is an advantage.  

The group has successfully performed several projects using 454- and Illumina technologies. We recently completed a reference sequence for the sugar beet genome (http://bvseq.molgen.mpg.de). We are a multidisciplinary team and offer work in a lively and friendly atmosphere and state-of-the art computing infrastructure. We are looking forward to expanding our team by a dedicated and strongly motivated person with distinct interest in the challenges of modern sequencing technologies.

The position is initially available for one year. The working place will be at the Center for Genomic Regulation (http://www.crg.es) in Barcelona/Spain. It is located at the seafront close to the Olympic harbor and combines excellent science with an inspiring environment in the heart of Barcelona with its cultural attractions, beach and metropolitan flair. The employment contract will be concluded with the Max Planck Institute for Molecular Genetics in Berlin/Germany. The salary will be according to the German collective agreement for the public service (TVöD), depending on academic level and previous experience.

The  Max  Planck  Society  is  committed  to  employing  more  handicapped  individuals  and  especially encourages them to apply. The Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.

Send application to: 
For informal inquiries by e-mail, please contact Dr. Heinz Himmelbauer (himmelbauer@molgen.mpg.de). Applications including summary of Master's and PhD theses, publication list, and contact details for three references should be sent by August 16, 2013 via e-mail to:
 
job-1312@molgen.mpg.de

Biochemist Postdoctoral Fellow United States

Under the general direction of the principal investigator, plan and carry out experiments designed to identify and characterize pathways and processes in sulfate reducing bacteria (SRB) which are targeted by environmentally relevant stresses. Specific attention will be focused on understanding the range of factors responsible for iron sulfur cluster cofactor biosynthesis and repair in SRBs.

SPECIFIC RESPONSIBILITIES:

• Characterize strains of Desulfovibrio vulgaris Hildenborough which possess null mutations in predicted FeS cluster biosynthesis components using biochemical assays for FeS enzyme activities and phenotypic screens.
• Perform chemogenomic fitness profiling of D. vulgaris mutants, using appropriate stress conditions, and contribute to the development of genetic interaction screening techniques which utilize a next generation sequencing based assay.
• Identify and characterize additional genes associated with FeS cluster biosynthesis and other systems linked to energy generation and metal homeostasis using chemogeneomic and genetic interaction fitness profiling techniques. Communicate with informatics analysis and data management colleagues to ensure correct and efficient data integration and interpretation.
• Use advanced spectroscopic approaches (CD, EPR) to characterize proteins of interest where required.  
• Provide research support and assistance to other members of the laboratory as requested.
• Keep detailed records of experimental procedures and results and communicate data to group and PI via individual and group meetings.

To apply

For full consideration, follow the link below to job posting and apply directly to Berkeley Lab.  As part of the online application process, please complete a profile, including uploading attachments relevant to the opportunity. 

https://lbl.taleo.net/careersection/2/jobdetail.ftl?lang=en&job=76019

Berkeley Lab is an affirmative action/equal opportunity employer committed to the development of a diverse workforce.

International fellowships to integrative biology postdocs in omics 2013 Belgium

VIB offers international fellowships to integrative biology postdocs who have advanced skills in omics technologies.

The omics@vib postdoc program offers a highly stimulating and multicultural environment. Embedded in excellent research groups, you will be working on breakthrough science, with access to cutting-edge technologies, three years secured funding and personal career assistance.

For the current omics@vib call, VIB provides 5 positions for integrative biology postdocs. Many VIB laboratories are suggesting an integrative biology topic for this program as indicated in the list below. You are free to select the topic of your own choice from the list and to design a 3 years postdoctoral project addressing this topic.

• Bioinformatics / Genomics / Proteomics / Structural Biology
• Cancer
• Cardiovascular Research
• Immunity / Inflammation
• Microbiology
• Neuroscience
• Plant Biology

ADMISSION REQUIREMENTS 

Nationality
VIB International Postdoc program “OMICS@vib” is open to applicants from all nationalities.
Applicants should not have been carrying out research in Belgium for more than 12 months during the last 3 years before the deadline of the program on 15/9/2013.
Postdocs selected for this program should be able to start their postdoc project before 1/6/2014.

University degree
Applicants must hold a PhD degree before the start of the fellowship, but not necessary when applying.

Publication record
Applicants must have a proven record of research accomplishments and at least one original first author publication (including joint authorship), either published or accepted in an international peer-reviewed journal with high recognition in the field.

Age
Candidates should not have more than 5 years of postdoc experience at the moment of the deadline 15/9/2013.

Career Break
One additional year will be taken into account for every childbirth or any other officially stated career break reason (caring for sick children or parents, additional studies…)

Language
English is used in all VIB laboratories for oral and written scientific communication. Candidates must deliver proof of a solid English working knowledge. Adding TOEFL test results in your cv is recommended.

Please go to www.vib.be/omics and follow carefully the different steps during the preparation stage and final submission stage of your project application. Use English during all stages of this application.

Postdoc Position in Bioinformatics and Computational Biology 2013 USA

The Menden-Deuer and Rynearson labs at the University of Rhode Island invite applications for a Postdoctoral Research Associate in bioinformatics and computational biology. Candidates will be selected based on overallexcellence, including academic qualifications, letters of recommendation, and prior skills.

Project Overview:

This project aims to examine, quantify and understand gene expression in marine plankton. Plankton are single-celled eukaryotes that form the base of marine food webs and are therefore critical to the health and well-being of the world’s oceans. This project represents an opportunity for a talented and creative postdoctoral researcher to work with sequencing data from ecologically important organisms. There will be opportunities to develop new or utilize the most recent algorithms for transcriptome assembly and mapping, particularly because most plankton genomes have not yet been sequenced.

Datasets include Illumina sequencing of plankton transcriptomes from multiple species and experiments under different conditions. The successful candidate will lead the project on the de novo analysis of transcriptomic data, which includes setting up and/or using available computational pipelines for transcriptomic data processing, identifying novel ‘high-responder’ genes and statistical comparison of multiple single-cell transcriptomes. The first dataset is ready for analysis.

Responsibilities and Duties:

The postdoctoral associate will be primarily responsible for analysis of the high-throughput sequencing component of the project (transcriptome sequence data). Responsibilities also include dissemination of results in publications and presentations and a willingness to assist with proposal preparation. The individual will be required to contribute to the functioning of the lab, assist with graduate and undergraduate student mentoring and help to develop future research projects.

Appointment:

The position is for 12-months initially, commencing August or September 2013 and renewable depending on performance. The successful candidate will receive training in research collaboration, presentation and publication of results, and outreach and mentoring. There will be opportunities for development of additional research projects and proposals.

Qualifications:

Candidates are required to have a Ph.D. degree by August of 2013 in Computer Sciences, Statistics, Biology or a related field. Excellent command of the English language (written and verbal) and quantitative analytical skills are essential. Candidates should possess demonstrable experience with the analysis of high throughput sequencing data including strong programming skills. We prefer candidates who have an excellent background in statistics and data mining.

To Apply:

Applications must include (1) a maximum 3-page statement of experience, career goals, research vision and interests; (2) curriculum vitae, (3) reprints of relevant publications and (4) names and addresses of three referees willing to write confidential letters of recommendation.

All materials should be emailed as a single pdf document to:rynearson@mail.uri.edu with ‘PostDoc Application’ in the subject line.

Candidates will be selected based on overall excellence, including academic qualifications, letters of recommendation, and prior skills, experience, and research goals that are compatible with the goals of the funded research. The position is compensated through a competitive salary and excellent benefits package. Please email rynearson@mail.uri.edu with additional questions about the position.

Research will take place on the shores of Narragansett Bay, RI at the URI Graduate School of Oceanography. The labs are conveniently located along the eastern seaboard with easy access to Amtrak and major airports. The candidate will benefit from existing collaborations with researchers in computational biology both nationally and internationally.

Closing date: For full consideration, applications should be received by July 1, 2013.

 For More Information

Postdoc Position in Bioinformatics and Computational Biology USA 2013

We have an opening for a bioinformatics scientist to support development, regulatory, and discovery needs for infectious disease therapeutics. These include deep sequencing of viral and bacterial pathogen DNA from clinical trials to discover and analyze resistance mutations, analysis of host-pathogen interactions in clinical samples and preclinical models, and genomic analysis of both individual bacterial species and bacterial communities. Contribution to regulatory filings will be expected. Close interactions with bioinformatics and infectious disease scientists will be required to achieve these goals.

The successful candidate will become an important member of teams developing breakthrough and life-saving therapies. High levels of drive, innovation, attention to detail, independence, and accountability will be required for success, along with flexibility to work with diverse teams that encompass all aspect of drug development. There will be opportunity and expectation to develop new computational methods, discover fundamental new understand and actively publish research results.

Genentech has one of the largest and most innovative bioinformatics departments in industry, and an unsurpassed ability to develop science into life-saving therapies. This is a great opportunity to do science at the highest level in the service of saving human lives.

Qualifications:

• PhD in biological or computational sciences with a minimum of 2 years post-PhD experience.
• Experience in Microbiology or Immunology.
• Strong demonstrated ability to deliver impeccable work on strict deadlines, with diligent attention to detail
• Expertise in statistics
• Bioinformatics programming ability including scripting of analysis workflows, experience in R and bioconductor a major plus.
• Experience in analysis of next-generation sequence data
• Demonstrated ability to work in cross-functional teams and to learn quickly outside of your core expertise area
• Familiarity with drug development and the clinical regulatory landscape will be considered a plus.

Desired Attributes:

• Experience in regulatory environment, FDA filings
• Experience in drug development
• Working with validated systems

For More Information 

Postdoctoral Position in Bioinformatics 2013 USA

A postdoc position in bioinformatics is open in Dr. Tao Liu’s lab at University at Buffalo(a.k.a SUNY Buffalo) under Department of Biochemistry. This newly established laboratory is interested in developing innovative algorithms for genomics data and building integrative bioinformatics knowledgebase to understand transcriptional and epigenetic regulation in development and various disease models. Current projects include a continuing development on one of the most popular ChIP-seq algorithms — MACS.

Requirements:

Qualified candidate should have a Ph.D degree in related field including but not limited to Bioinformatics, Genomics, Biology, Physics, Statistics, or Computer Science. Strong programming skills are expected (Python|Perl|Java|C|C++ & R). Good communication skills of speaking and writing in English are required. A strong publication record and extensive experience of large-scale bioinformatics data analysis is preferred. Most importantly, successful candidate should have motivation and enthusiasm on scientific research.

How to Apply:

To apply, please email your CV, a letter of interest with one-page statement of your career goal, and contacts of at least three references to Dr. Tao Liu (tliu4@buffalo.edu) with subject containing ‘Postdoctoral Application’.

Postdoctoral position in Biomedical Informatics 2013 USA

After seven productive years at the University of California, Los Angeles, our lab (Neural Systems and Dynamics Lab) is moving to the University of California, San Francisco in September 2013.  With this move, we expect to expand our R&D project portfolio and collaborative network.  A key mission of our lab has been to develop new algorithms of analyzing Big clinical data to more effectively address significant clinical problems.  Several postdoctoral positions will become available in Fall 2013, for at least two years, for candidates with strong skills in at least one of the following areas: applied math, machine learning, data mining, signal processing, mathematical modeling, biostatistics, neural engineering.  Candidates with particular interest in applying their analytic and informatics skills toward building biomedical and healthcare applications will surely enjoy the range of projects that we are pursing. The lab will also provide opportunities and incentives for those candidates with adequate levels of skills and experience to discover and lead projects on the UCSF campus where bioengineering talents are highly sought after.
Interested candidates can email the PI:
Xiao Hu, Ph.D.
Director, Neural Systems and Dynamics Lab
Associate Professor
Email: xhu@mednet.ucla.edu or xiao.hu@nursing.ucsf.edu
Also interviewing opportunities are available at the upcoming 35th IEEE EMBS annual meeting in Osaka Japan.

For Further Information

Postdoctoral Position in Genomics 2013 USA

Postdoctoral positions are available with Jeffrey Kidd in the Department of Human Genetics and Department of Computational Medicine and Bioinformatics at the University of Michigan Medical School. These positions are focused on population genomic analysis to learn about the demographic history of populations and species and how demography interacts with selection to create observed patterns of variation. Multiple projects are available in a number of systems, including human populations (particularly African populations), dogs, and other species.

Requirements:

The applicant should have a Ph.D. in genetics, ecology and evolution, anthropology, molecular biology, bioinformatics, computational biology or a related field and have experience in the analysis of genome-wide data. Excellent written and oral communication skills are required.

Successful applicants will be part of a cutting-edge research program in genomics with ample opportunities for collaboration with researchers at theUniversityofMichiganand around the world.

How to Apply:

To apply, send a CV, cover letter describing your research experiences and ongoing research interests, and contact information for up to three references to Jeffrey Kidd at jmkidd@umich.edu

Postdoctoral position Bioinformatics 2013 USA

One postdoctoral position is available immediately in the Neurological Research Institute (NRI) at Baylor College of Medicine, one of the top medical schools in the United States. The NRI will bring together world experts in neuroscience, computer scientists and applied mathematics to pursue collaborative, interdisciplinary basic and translational research on a variety of neurological and neuro-developmental disorders. The successful candidate will be expected to develop and utilize bioinformatics algorithms to interpret and integrate various microarray and next-generation sequencing data for a better understanding of the molecular mechanisms underlying human neurological diseases.

Qualifications
The ideal candidate should have 1) a Ph.D. in Bioinformatics, Computer Science, Statistics or related field. 2) experience in machine learning, convex optimization, artificial intelligence and/or mathematical modeling. 3) strong skills in at least one programming language (MATLAB, R, JAVA or C/C++) and/or large-scale data analysis skills.

To apply

Zhandong Liu, Ph.D.

Assistant Professor

Department of Pediatrics Neurology,

Jan and Dan Duncan Neurological Research Institute

Baylor College of Medicine

One Baylor Plaza, Room 319C

Houston, TX 77030

Email: zhandong.liuATbcm.edu

China: Postdoc positions to study noncoding RNA functions 2013

Postdoc positions are available immediately to study noncoding RNA functions in development of neural stem cells and in formation of human and mouse brains (Bian et al., 2013 Cell Reports; Otaegi et al., 2011, J. of Neurosc.; Kawase-Koga et al., J. of Cell Science). Candidates with a strong background in RNA biochemistry, mouse genetics, stem cell culture, bioinformatics, and/or molecular biology are strongly encouraged to apply. Competitive salary and benefits.

Candidates may take a short training at Cornell University Weill Medical College at New York City, and will be working full time at Shanghai Jiao Tong University in Shanghai, China. Successful candidates have the opportunity to be promoted to positions equivalent to Assistant or Associate Professor in a short period time.

Please send cover letter, research interests, CV, publications and three names who can provide recommendation letters in Word or PDF files by email to Dr. Sun at taosun11@sjtu.edu.cn or tas2009@med.cornell.edu.

NIH-funded cancer genomics post-doctoral research position

An NIH-funded cancer genomics post-doctoral research position focusing on integrative analysis of next generation sequencing (NGS) data is available within the Maher lab (www.maherlab.com). To fully translate genome-based discoveries into the clinic our group is associated with the Department of Medicine and The Genome Institute (TGI) at Washington University. The successful applicant will focus on applying and developing computational and statistical tools to analyze whole genome and transcriptome sequencing data from cancer patients.

Applicants should have a graduate degree in biology, bioinformatics, computational biology, or related field with a solid background in programming and statistics. Candidates should be comfortable working on UNIX/Linux operating system, program with Perl and/or Python, and familiar with statistical analysis packages (SAS, R, or Bioconductor). Also expected to be familiar with bioinformatics tools and genomics databases. Previous experience in cancer genomics would be an advantage but is not essential.

The successful candidate will be self-motivated, eager to acquire new knowledge and skills on a regular basis, and must demonstrate critical thinking skills. The ability to analyze and interpret results to communicate with others and produce scientific publications is required.

Review of applications will begin immediately and will continue until the position is filled.

To apply

Please send a CV, including a list of three references, to Dr. Christopher Maher (cmaher at dom dot wustl dot edu).

Molecular Microbiology Postdoctoral research position 2013 - United States

A postdoctoral research position is available in the laboratory of Dr. Ravi Barabote (http://www.uark.edu/ua/barabote/) in the Department of Biological Sciences at the University of Arkansas. The successful candidate will be involved in research focused on genome-level understanding (transcriptomics and proteomics) of the interactions of thermophilic cellulose-degrading bacteria with plant cell wall. The research project involves extensive transcriptomic (using RNAseq) and proteomic analyses of thermophilic cellulolytic bacteria exposed to a variety of growth conditions, as well as the usage and development of bioinformatics approaches/tools to integrate and analyze the high-throughput expression data. Additionally, target genes identified from these analyses will be genetically engineered in the bacteria to study function. The goal of the project is to develop a deep understanding of the shifts in bacterial physiology and metabolism in response to various growth conditions.


Minimum Qualifications: A Ph.D in the areas of molecular microbiology or closely related fields with strong research background in bacterial physiology and genomics is required. Ability to work independently as well as in a team environment is essential. Candidates must possess good written and verbal communication skills. The candidate will be expected to work in a team environment, assist other researchers in the lab, prepare manuscripts for publication, and contribute to grant proposal preparation.


Preferred Qualifications: Documented evidence (eg. publication record) of prior experience in bacterial genetics, functional genomics, and bioinformatics is preferred. Experience in analyzing bacterial genome and transcriptome data, and experience in bioinformatics programming is highly desired.


The University of Arkansas is an Affirmative Action/Equal Opportunity Employer. The University welcomes applications without regard to age, race, gender, national origin, disability, religion, marital or parental status, veteran status, genetic information or sexual orientation. Applicants must have proof of legal authority to work in the United States. All applicants are subject to public disclosure under the Arkansas Freedom of Information Act.

To apply

To apply for the position, please email your CV with a cover letter and have three letters of recommendation sent directly to Dr. Barabote (barabote@uark.edu). Applications can also be mailed to the following address: Dr. Ravi Barabote, Department of Biological Sciences, 850 W Dickson Street, SCEN 601, University of Arkansas, Fayetteville, AR 72701. For additional information, please visit https://jobs.uark.edu/applicants/Central?quickFind=54030

Expires: May 11, 2013

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Postdoctoral level position - Bioinformatics/ Computational biology - United States

The Shapiro Laboratory at Columbia University in New York City, working together with the NIH Vaccine Research Center (VRC), in Bethesda, MD, seeks a postdoctoral level researcher in computational biology and bioinformatics for a position starting on or about July 1, 2013. Work will involve analyses of high-throughput sequencing results of the antibodies produced HIV infected patients. The goal is to understand the maturation of these antibodies from their genomically-encoded precursors in order to inform rational vaccine development. (See for example Science, 333, 1593, 2011; Front Microbiol. 3, 315, 2012).

Funding for two years is guaranteed, and may be extended for up to five years by extramural support. We are looking for creative, self-motivated individuals who are interested in applying computational tools to challenging problems associated with the design of vaccines. The individual should be well-organized as keeping track of numerous large sequence data sets will be required.

Applicants who meet the following requirements will be considered for the positions:


A Ph.D. degree in bioinformatics / computational biology / computational chemistry or a closely related field

•        Proficiency in at least one programming language and script writing in Perl or Python
•        Excellent oral and written communication skills
•        Clear sense of organization, purpose and accountability
•        Experience with or knowledge of antibodies is desirable, but not required

To apply

 Interested applicants should send a current CV and three letters of reference to Prof. Lawrence Shapiro (email: LSS8@columbia.edu).

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Cell biology postdoctoral position - 2013 United States

A postdoctoral position is available in our lab at the Stem Cell Institute, University of Minnesota. We have recently discovered that a fusion protein between the transactivation domain of the MyoD protein and the pluripotency factor Oct4 can drastically increase the efficiency of making iPS cells (Stem Cells, 2011, 29:1349; PLoS ONE, 2012, 7: e34149; PLoS ONE, 2012, 7: e39022). Developing this study, we are now studying the roles of long noncoding RNAs in pluripotency of ES cells and iPS cells, as well as in oncogenesis using RNA-ChIP and RNA-seq. The recently developed TAL effector technology will also be incorporated. Strong interest or experience in bioinformatics (microarray, RNA-seq and various gene analysis programs) is preferred, in addition to the standard cell culture and molecular biology techniques. Understanding of stem cell biology is also preferred.
To apply

 Please email CV and names of three references to below.

    

    Nobuaki Kikyo M.D., Ph.D.

    Associate Professor of Genetics, Cell Biology and Development

    University of Minnesota

    Stem Cell Institute

    Minneapolis MN 55455

    Phone 612-624-0498

    FAX 612-624-2436

    Email kikyo001@umn.edu

Molecular Biomarkers - Postdoctoral position 2013 France

High-throughput "omic" technologies represent promising opportunities to find new disease biomarkers because of their comprehensiveness and their complementarity. However, integration of such massive and highly heterogeneous data is a bioinformatic challenge. First, for each experiment, raw data must be processed to obtain a n sample x p variable table of signal intensities (e.g. peak detection, quality control, normalization). Second, innovative statistical methods must be developed to extract relevant features from those n << p matrices. Third, additional database information regarding interactions between molecules must be taken into account in collaboration with biologists to validate the identified biomarkers and fingerprints.

Project:

The Biomargin European project aims at finding new molecular biomarkers of renal graft injuries and at developing algorithms to assist clinicians in detecting and interpreting chronic graft dysfunction. As leader of the workpackage "Data integration and disease prediction modeling", our team will first be responsible for statistical integration of the datasets (transcriptomic, proteomic and metabolomic) provided by the clinical partners. Second, the annotated candidate biomarkers will be validated through pathway analysis (e.g. with the Ingenuity software). Third, a model of disease progression based on the selected fingerprints will be developed and validated on a prospective cohort of transplant patients.

Job description:

In our laboratory, the post holder will use multivariate statistical techniques (multi-block analysis, orthogonal partial least-squares) for data integration and biomarker selection. All information regarding the selected molecules will be stored in a dedicated database. Once the candidate markers have been validated by the experimental partners, machine learning algorithms will be developed for the prediction of patient status.

 Profile:

 Interested applicants should hold a PhD in biostatistics or bioinformatics and and be used to programming with the R software. The candidate should be highly motivated by applied trans disciplinary team work aiming at clinical applications.
 
Our offer:

    1-year contract (renewable once).

    Net salary: about 2200 €/month, depending on experience.

Note:

    Funding is dedicated to PhD candidates under 30 years old.

To apply

    Please send your CV and your letter of motivation to:
    Etienne Thévenot (etienne.thevenot@cea.fr)
    Laboratory of Data Analysis Tools
    CEA Saclay, F-91191 Gif-sur-Yvette, France

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Post-doctoral position in Computational/ Systems biology 2013 - USA

Applications are invited for a post-doctoral position in Computational and integrative Systems biology in the Ng Lab at Massachusetts General Hospital (MGH) and Harvard Medical School (www.massgeneral.org/gastroenterology/research/researchlab.aspx?id=1553).

The lab is situated in a vibrant and highly collaborative multi-disciplinary research environment within the Center for the Study of Inflammatory Bowel Disease (CSIBD) (www.massgeneral.org/csibd/) at the MGH which is currently ranked the nation’s top hospital. This lab benefits from close collaborations on both computational and experimental fronts within the CSIBD and state-of-the-art high-throughput screening and computational platforms at the Broad Institute of MIT & Harvard. Our lab utilizes integrative systems approaches involving computation and high-throughput experimentation (RNA interference (RNAi) and chemical biology screens, transcriptomics, proteomics, metabolomics, and data from genome-wide association studies (GWAS)).

We are seeking creative and highly motivated applicants who have a strong interest in pursuing computational and systems-level research into understanding microbial sensing, biological circuits, networks and pathways in regulating immune responses to microbes or their dysregulation in complex human genetic diseases, including Crohn’s disease, ulcerative colitis and Type I diabetes. This position also provides opportunities to participate in exciting multi-disciplinary research programs investigating the interplay of host genetics and environmental factors (including pathogens and gut microbiota) in influencing immune responses and disease outcomes.

    Applicants should have a Ph.D., with a quantitative background in one or more of the following:
     • computational biology/bioinformatics,
     • computational statistics/physics/mathematics,
     • computer science/machine learning/data-mining, or
     • engineering/signal processing

Programming proficiency in Java/C/C++, Python/Perl, and MATLAB/R is required. Additionally, prior experience in Next-Generation sequencing (NGS)/RNA-seq analysis, and genome-wide epigenetic profiling, as evidenced by scientific publications in peer-reviewed journals, would be a plus. The successful candidate will be a collaborative individual with the ability to work independently, creatively, resourcefully, meticulously, and also multi-task, support team goals and drive team performance. Excellent written and verbal communication skills are essential.
To apply

Interested applicants should email your CV with contact information of three referees, and a cover letter outlining your career goals to Dr. Aylwin Ng (ang@ccib.mgh.harvard.edu). Expires: May 05, 2013

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Computational biology Postdoctoral Position 2013 - France

    Employer:INSERM (Institut National de la Santé et de la Recherche Médicale)
    Location: Paris, France
    Compensation: to negotiate; relocation allowance to be discussed
    Job Type : Contract, promotion to a permanent position possible
    Term of Position: 24 months, promotion to a permanent position to be discussed
    Posted: April 3, 2013
    Application Deadline : Open until filled

    Description:

    We are looking for a candidate with strong Machine Learning background to join the Nutriomics team. The laboratory is associated with the INSERM (National French Institute of Medicine and Health), University Pierre et Marie Curie, and ICAN ( Institute of Cardiometabolism and Nutrition).

    About the position:

    Candidates should have a good background in probabilistic graphical models, statistical learning, and Bayesian inference (generative/discriminative setting). PhD degree in mathematical, computer modeling, bioinformatics/biostatistics, or related science.

    Experience in analyzing large volumes of data is good to have.

    Interest in biology. Background in computational biology and experience with biological datasets are desirable but not obligatory.

    Good spoken and written English, excellent communication skills, mature and motivated, as well as a pro-active attitude, creative and multitasking.

    Experience in developing tools or packages in R, Maltlab, etc. is expected.

    About the Nutriomics team:

    The Nutriomics team is focused on understanding of the patho-physiological mechanisms associated with obesity at its different stages of natural evolution. We are studying mechanisms of regulation in response to environmental variations and changes, and we are interested in integration of complex clinical and biological data.
To apply

    Applicants should email to Prof. Jean-Daniel Zucker and Prof. Karine Clement at Recruitment@fondation-ican.com with subject line “Postdoc application” and include a cover letter, a CV, and a list of at least two references.

Postdoctoral position to study uterine leiomyoma 2013 - United States

One of the top-ranked universities in the country, Northwestern University, combines innovative teaching and pioneering research in a highly collaborative environment that transcends traditional academic boundaries. Northwestern provides students, faculty, and staff with exceptional opportunities for intellectual, personal, and professional growth. A postdoctoral position is available in the laboratory of Erica Marsh, MD MSCI in the Dept. of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University.

We are looking for postdocs who are interested in investigating studies on uterine leiomyoma that focus on (1) miRNA (2) hypoxia, and/or (3) tissue microenvironment in disease progression.

Candidates must have a strong background in molecular biology techniques and strong writing skills. Experience with microarrays, bioinformatics, cell and tissue immunohistochemistry, immunofluorescence, is preferred.
To apply

 Interested applicants should submit a copy of their CV, cover letter and a list of at least three professional references to Ms. Angela Scott via email: ascott@nmff.org.

 Northwestern University is an Affirmative Action/Equal Opportunity Employer.  Hiring is contingent upon eligibility to work in the United States.  Women and minorities are encouraged to apply.





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Fungal molecular biology post doctoral position 2013 - UK

A post doctoral position is available in the Polyketide Research Group at the University of Bristol, working with Professor Russell Cox, Professor Tom Simpson and Professor Chris Willis in the School of Chemistry and Dr Andy Bailey and Dr Colin Lazarus in the School of Biological Sciences.

A collaborative research project, funded by BBSRC and Syngenta, will link research groups at the Universities of Bristol, Cambridge, Manchester and Warwick with the aim of investigating and exploiting microbial resources for the development of new agrochemicals and other bioactive compounds. The project will focus on rapid genome sequencing of numerous microbes that are known to produce secondary metabolites with useful biological properties, such as selective herbicides and fungicides.

The post doctoral Research Assistant will require skills in fungal molecular biology, natural products chemistry and bioinformatics with particular reference to microbial genomics. The project is multidisciplinary and highly collaborative and will involve regular direct interaction with the other academic and industrial partners. The successful candidate will thus require the ability to prepare reports, research publications and effective presentations. The appointee will join a large multidisciplinary group with interests in all aspects of fungal secondary metabolism and with a strong track record of research success.
Closing Date: Midnight on 17 May 2013

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Postdoctoral Fellow in Bioinformatics and Stem Cell Biology - USA

We are seeking a highly motivated postdoctoral fellow to study stem cell biology using Systems Biology approaches in the Department of Neurosurgery, and Center for Stem Cell and Regenerative Medicine at the University of Texas Medical School at Houston.

Our laboratory combines stem cell biology and systems-based approaches involving functional genomics and next-generation sequencing technologies including RNA-Seq and ChIP-Seq and functional tests to unravel gene transcription and regulatory mechanisms governing neural differentiation. We are currently pursuing basic and translational research in neural repair and neuroprotection in regenerative medicine. The other area of our research interest lies in the studies of the regulatory networks of hematopoietic precursor cell self-renewal and differentiation.

Requirements:
Qualified candidates should:
• Have strong background and skills in bioinformatics, statistics and next-generation sequencing data analysis; biological experimental background and knowledge are preferred
• Demonstrated proficiency as evidenced by relevant publications in peer-reviewed journals and is interested in acquiring new skills.
The candidate will have the opportunity to pursue highly collaborative projects with significant translational impact, alongside with stem cell researchers and clinicians.



About us:
Our lab is located in the beautiful new facility of the Brown Foundation Institute of Molecular Medicine in the Texas Medical Center. Texas Medical Center is one of largest medical complex in the world and provides access to the more than 40 member institutions, including two medical schools, four schools of nursing and 13 renowned hospitals. Many scientific and educational opportunities are available in the metropolitan area of Houston as well as cultural, entertainment and sports activities.

How to Apply:
Please email your application including a CV, a summary of previous research, a statement of interest and career objectives, and contact information of 3-5 referees to:
Dr. Jiaqian Wu, Ph.D.
Department of Neurosurgery
Center for Stem Cell and Regenerative Medicine
The University of Texas Medical School at Houston
Email: Jiaqian.Wu@uth.tmc.edu