USA: Postdoctoral position immunology, molecular, or cell biology

A postdoctoral position is open to study homing properties of T cell subsets in melanoma and vitiligo, in the laboratory of Dr. Caroline Le Poole. Highly motivated recent graduates (PhD and/or MD) with a strong background in immunology, molecular, or cell biology are encouraged to apply. Previous experience working with mice is preferred. Loyola is an equal opportunity and affirmative action employer/educator and is committed to drug free and smoke free workplace.

Our research is conducted in the Oncology Research Institute on the Loyola University Chicago Health Science Campus, located in the west suburbs of Chicago, Illinois.

To apply: Interested applicants may send CV, a brief description of research interests and career goals, and contact information of three references via email to: ilepool@lumc.edu.

USA: Postdoctoral position in translational gene therapy and cell therapy

A Research Associate/postdoctoral position is available in translational gene therapy and cell therapy. This position is available for a scientist (PhD, MD, and/or DVM) interested in the design and use of cell based therapies to modulate immunity for a variety of disease conditions. This position will focus on the development of novel strategies to alter immunity through the use of genetically altered immune cells in the context of cancer, autoimmunity, and/or infection. The overall aim is to develop novel immune therapies, demonstrate efficacy and mechanisms of action in preclinical studies, which will lead to Phase I clinical trials in patients. The ideal candidate will have a background in gene therapy, inflammation, molecular immunity, and in vivo techniques. Experience with autoimmunity, immunotherapy, and viral transduction would be helpful. Good communication skills, leadership potential, and the ability to work in a team are essential. Salary will be commensurate with experience.

To apply: Interested applicants should send a single PDF document by email that contains: a brief summary of research interests and career goals, curriculum vitae, list of publications, and the names of three professional references to:

Dr. Charles Sentman, Department of Microbiology and Immunology, The Geisel School of Medicine at Dartmouth, 6W Borwell Bldg., One Medical Center Drive, Lebanon, N.H. 03756, U.S.A; email: charles.l.sentman@dartmouth.edu; website: http://dms.dartmouth.edu/faculty/facultydb/view.php?uid=139.

USA: Multiple postdoctoral positions in cell and molecular immunology

Multiple postdoctoral positions are available immediately to study cell signaling in the immune system at the Baylor Institute for immunology research (BIIR).

The project requires expertise in cell and molecular immunology. We use mouse models of autoimmunity, allergy and cancer. For more information see Venuprasad K et al. Nat Immunol. 2008, Venuprasad K et al. J Clin Invest. 2006, Chang L et al. Cell. 2006, Jeon MS et al. Immunity. 2004, Venuprasad, Cancer Res.2010, Peng D et al. J Immunol. 2011, Ahmed N et al. Nat. Immunol. 2011, Zeng M et al. (manuscript under preparation), Ahmed N et al. ( manuscript under preparation). The applicants with one or more years of postdoctoral experience are preferred but fresh PhD’s are welcome. This is an outstanding opportunity for enthusiastic and hard working postdocs. The environment and the facilities at the at BIIR and the Sammons Cancer center in Dallas, TX is exceptional.

To apply: If interested, please send a CV to Dr. K Venuprasad: Venuprasad.poojary@baylorhealth.edu.

Competitive salary will be offered for the right candidates.

Dean’s Postdoctoral Fellowship at Harvard Medical School

The Dean’s Postdoctoral Fellowship at Harvard Medical School is a 2-year postdoctoral research fellowship sponsored by the Office for Diversity Inclusion and Community Partnership and the Office for Postdoctoral Fellows.

The Dean’s Postdoctoral Fellowship is accepting applications from postdoctoral scientists, particularly from underrepresented and disadvantaged backgrounds, in the fields of basic or social sciences. The Dean’s Postdoctoral Fellowship will prepare postdoctoral researchers for cutting-edge research careers. Postdoctoral fellows will benefit from the highly innovative and creative research environment at Harvard Medical School that emphasizes scientific rigor, collaboration and the pursuit of excellence in science. This fellowship will position the right candidate to make major contributions as scientific and societal leaders.

Applications are being considered on a rolling basis for positions in the following departments on the Quadrangle:

• Biological Chemistry and Molecular Pharmacology
• Cell Biology
• Genetics
• Global Health and Social Medicine
• Health Care Policy
• Microbiology and Immunobiology
• Neurobiology
• Stem Cell and Regenerative Biology
• Systems Biology
• Wyss Institute for Biologically Inspired Engineering

ELIGIBILITY - Candidates must have:

• completed MD, PhD, ScD, or equivalent in the basic or social sciences by the start date of this research fellowship
• less than five years of relevant postdoctoral research experience
• United States citizenship or permanent residency
• demonstrated motivation for career advancement in research and scholarly excellence

Ordinarily candidates will have at least one first authored publication and some conference presentations. Graduates of Harvard Medical School PhD and MD programs should not apply to work with faculty of the department that granted their doctorate.

ONLINE APPLICATION - Applications must be submitted online and are currently accepted on a rolling basis. Qualified applicants will be selected by the laboratory or program and a committee with representatives from various departments.

To apply: To apply or learn more about this opportunity, please visit:http://www.hms.harvard.edu/dcp/deanspdfellowship.

For more information, please contact: Brian L. Anderson, Program Manager, Harvard Medical School, Office for Diversity Inclusion and Community Partnership, 164 Longwood Avenue, 2nd Floor, Boston, MA 02115-5818; Tel: 617-432-1083; Fax: 617-432-3834; E-mail: dcp_deanspostdoc@hms.harvard.edu.

Post-doctoral positions cell biology/ molecule imaging/ brain slice electrophysiology

Post-doctoral positions are available starting fall 2013-spring 2014 at the Institute for Interdisciplinary Neuroscience in the group “dynamic organization of synapses”, headed by Daniel Choquet and funded by grants from the European Research Council (ERC) and the Ministry of research (ANR) to work in an interdisciplinary environment on the molecular and cellular mechanisms of synapse organization and plasticity, in particular combining super-resolution technique and electrophysiology on cell cultures and brain slices. (See Heine et al. Science 2008, Opazo et al, Neuron 2010, Nair et al. J. Neuro 2013).

Candidates less than four years after their PhD with excellent past-record of achievement will have expertise in one of the following: cell biology, high resolution or single molecule imaging, brain slice electrophysiology.

Projects range from the analysis of AMPA receptor organization and trafficking at the single molecule level and their physiological function to the development of new high resolution imaging methods and bio-sensors.

Application and informal information may be sought, or pre-application discussions conducted, via e-mail.
Application should include a letter of motivation, a CV and a short summary of your current researches and center of scientific interest.

More details at http://www.iins.u-bordeaux2.fr/research-teams/daniel-choquet-team and http://www.bic.u-bordeaux2.fr/.

To apply: Please send CV and two letters of recommendation to: IINSrecruit@gmail.com.

Contact: Daniel Choquet, Interdisciplinary Institute for Neuroscience, IINS, CNRS UMR 5297, 146 rue Léo Saignat, 33077 Bordeaux Cedex, France

USA: Postdoctoral fellow position in immunology, molecular, or cell biology

A postdoctoral fellow position is open to study advancing immunotherapeutic approaches in hepatocellular carcinoma in the laboratories of Dr. Stephanie K. Watkins and Dr. Michael Nishimura. Highly motivated recent graduates (PhD and/or MD) with a strong background in immunology, molecular, or cell biology are encouraged to apply. Previous experience working with mice is preferred. Loyola is an equal opportunity and affirmative action employer/educator and is committed to drug free and smoke free workplace. Our research is conducted in the Oncology Institute of the Cardinal Bernardin Cancer Center, on the Loyola University Chicago Health Science Campus, located in the west suburbs of Chicago, Illinois. To apply: Interested applicants may send CV and the names, email addresses, and telephone numbers of three references via email to: swatkins1@lumc.edu.

Postdoctoral position cell signalling 2013, Germany

A PhD position and a postdoctoral position are available in project 1 (Feil) of the newly established DFG Research Unit FOR 2060. Project start is summer 2013. The Research Unit investigates the function of the intracellular signalling molecule, cyclic guanosine monophosphate (cGMP) in mammals, specifically in tissue degeneration and regeneration. Project 1 studies the role of global and local cGMP signals in growth control. We use fluorescence-based cGMP sensor proteins to visualize changes of the signalling molecule in living cells in real time. This will allow us to monitor the spatiotemporal dynamics of cGMP signalling under various conditions and to correlate the respective cGMP signals with associated alterations in the growth of cardiovascular and neuronal cells. The projects involve analyses at the molecular, cellular and whole organism level. Candidates should be interested to work at the interface of biochemistry and biomedicine, with a focus on cell signalling under native conditions. Experience in the fields of signal transduction, transgenic mouse technology, and/or live cell imaging would be an advantage.

For recent project-relevant publications of our group, see:
Original Article: Thunemann, Wen et al. (2013). Transgenic mice for cGMP imaging. Circ Res, in press.
Methods Article: Thunemann et al. (2013). Visualization of cGMP with cGi biosensors. Methods Mol Biol 1020, 89-120.
Review Article: Kemp-Harper & Feil (2008). Meeting report: cGMP matters. Sci Signal 1, pe12.

For further information, please visit www.cyclic-gmp.de or www.ifib.uni-tuebingen.de/forschung/feil.html.

Please send your application (including names/emails of 2 referees) to Prof. Dr. Robert Feil, University of Tübingen, Interfakultäres Insitut für Biochemie (robert.feil@uni-tuebingen.de).

Deadline for applications: 16 August 2013

UK: Postdoctoral Scientist position in biochemistry/ molecular microbiology/ cell biology

The mammalian gastrointestinal (GI) tract is home to complex bacterial communities. Most of the bacteria establish beneficial symbiotic relationships with their host, making important contributions to metabolism and digestive efficiency. The vast numbers of bacteria in the GI tract and their proximity to host tissues raise the question of how homeostatic host–bacterial relationships are established and maintained without eliciting potentially harmful immune responses.
The mucus barrier, antimicrobial proteins and IgA operate together to confine symbiotic bacteria towards the outer mucus layer and protect the epithelial surface by limiting bacterial penetration. This homeostatic interaction between mucus and gut commensals is critical to maintain gut health. Intestinal pathogens have evolved strategies for subverting and evading these barriers to access host tissues. By contrast, there is currently very limited knowledge of the mechanisms resident members of the intestinal microbiota interact with components of the mucus barrier.
Mucus-binding proteins (MUBs) are a class of cell-surface adhesins found in Gram-positive gut symbionts, shown to mediate interaction of bacteria to mucus. Building on our extensive preliminary data on the structural and biochemical properties of MUB, the purpose of this study is to determine the molecular and cellular basis of MUB interactions with receptors of the mucus layer, mucins glycans and mucosal antibodies and assess the potential of the impact of MUBs and IgA interaction on bacteria adhesion to mucus and IgA effector function, providing mechanistic insights into the regulation of gut microbiota homeostasis. Understanding the molecular basis of these processes will help understand how some bacteria strains exert intestinal health protection and devise intervention strategies to reinforce gut health.
This interdisciplinary project will benefit from the established international network of collaborations of the Lab in this area of research. In addition to the proposed experimental work, the post-holder will contribute to the research by interacting with research scientists and PhD students in the Group and by following up existing collaborations with scientists on the Norwich Research Park and with external collaborators, writing-up reports and publications, presenting at relevant meetings and Conferences. The post-holder will be encouraged to present his/her results to the general public by joining IFR-led Public Engagement activities. In addition, he/she will benefit from regular BBRSC-sponsored training courses in career development and transferable skills.

Key relationships
The post-holder will work in the Gut Health and Food Safety Programme and will be line-managed by Dr Nathalie Juge. He/she will work closely with PhD students and with research assistants , Louise Tailford and Donald MacKenzie in the Juge Group. The successful candidate will be expected to present work at internal Lab Programme and meetings and at Conferences.

Main Activities & Responsibilities

• MUB ligand characterisation in vitro and binding kinetics & thermodynamics
• Lactobacillus reuteri binding specificity to cell lines and in vitro tissue culture models
• MUB binding specificity to cell lines and host tissues
• MUB and MUB repeat purification and characterisation
• Writing-up reports, publications, presentations
• Contribute to Lab supervision

Education & Qualifications

• PhD biochemistry/molecular microbiology/cell biology or equivalent experience
• BSc in Biological Sciences
• Expertise in glycobiology
• Expertise in gut microbiology

Read Further about the position

Postdoctoral research position in cellular and molecular biology, especially RNA work, USA

Postdoctoral research position available immediately for highly motivated candidate to help develop gene expression approaches for biological dosimetry, and to study the effects of different radiation modalities (dose, dose-rate, LET, organ-specific effects).

The laboratory is part of the Center for Radiological Research (http://crr-cu.org/) in the Department of Radiation Oncology at Columbia University.  Some of the research will involve use of our Radiation Research Accelerator Facility (http://www.raraf.org/) located just outside New York City in Westchester County.

Successful candidates must have experience in cellular and molecular biology, especially RNA work, as well as excellent communication skills, and a high level of proficiency in one or more of the following areas:  radiation biology, microarray and bioinformatics, mouse work, biodosimetry.

Please be sure to include a statement of research interests, CV with publication list, and contact information for three references with application.  

Columbia University Medical Center is an Affirmative Action / Equal Opportunity employer.

To apply click here

Postdoctoral position in cardiovascular diseases 2013, Spain

Applicants must be experienced researchers with a doctoral degree related to medical/biological sciences and interest in cardiovascular diseases. Applicants must possess a strong publication record, with experience in molecular biology, cell biology and signaling.  Experience with animal models of regeneration and hematopoietic/cardiac stem cells is preferable.

We offer a 2 year contract with competitive salary according to the experience of the selected candidate. The CNIC has an advanced policy on matters of welfare benefits, with the most modern flexible remuneration systems.

To apply
Qualified applicants should submit an application by e-mail, including a letter outlining research interests, a CV, and the contact information of three referees, to Eduardo Bieger (ebieger@cnic.es)

http://www.cnic.es/en/inflamacion/metaloproteinasas/index.php

Postdoctoral fellow position in Immunology/ Cell / Molecular Biology/ Biochemistry at Germany

The research group „Inflammatory signalling in alloimmunity and infection“
at the 3rd Medical Deparmtment of Hematology and Oncology (Director: Univ.-Prof. Dr. Christian Peschel) at Klinikum rechts der Isar (Technische Universität München) is offering a position for a

Postdoctoral fellow
Our research group studies the interplay between innate and adaptive immunity in infectious
and malignant diseases and is situated in a highly stimulating research environment. Our
research is supported by the German research foundation and the Else-Kröner-Research-Foundation.

Applicants should have a MD or PhD or equivalent doctoral degree with at least 3 years of
proven research experience in Immunology, Cell / Molecular Biology or Biochemistry. Prior
experience with in vivo technologies will be of advantage. The ideal candidate should be a
highly motivated and goal-oriented researcher, provide a good publication record, be able to
work in a team as well as show some experience in the supervision of graduate students or
master students.
Payment is according to tarif (TV-L). We give priority to severely disabled applicants with essentially equal qualifications.

Please submit your complete application documents (including CV, motivation letter,
publication list and references - all documents within a single PDF file) via E-mail to:

PD Dr. med. Hendrik Poeck or Dr. med. Tobias Haas
III. Medizinische Klinik und Poliklinik
Klinikum rechts der Isar
der Technischen Universität München
Ismaninger Straße 22 ∙ 81675 München

Email: hendrik.poeck@lrz.tum.de or tobias.haas@lrz.tu-muenchen.de
Website:
http://www.med3.med.tu-muenchen.de/forschung/Grundlagenforschung/Tumorimmunologie/haaspoeck.html

USA: Postdoctoral research fellow position Immunology/ Cell Biology/ Biochemistry

One postdoctoral research fellow position is available in the Department of Pharmaceutical Sciences at the University of Oklahoma Health Sciences Center, College of Pharmacy, Oklahoma City. Dr. S. Awasthi’s research group is seeking a highly motivated and enthusiastic postdoctoral research fellow to study the immunomodulation and biological activity of Toll-like receptor 4-interacting SP-A regions and peptides in cell culture and animal models of both infectious and inflammatory diseases. In this position, the postdoctoral researcher will help elucidate potential mechanism(s) involved in host cell immunomodulation. Multi-disciplinary approaches are utilized in Dr. S. Awasthi’s research program including: 1) structural biology, 2) mammalian two-hybrid, 3) genetic transfection, 4) microbiological and immunological studies; and 5) contemporary biochemical and molecular biology techniques including Western blot/immunoprecipitation and confocal microscopy etc. The position is supported through NIH/NIGMS grant funds and University Growth fund. The initial appointment would be for 1 year with the possibility of renewal. Review of applications will begin immediately and the position will remain open until filled.

Qualifications

Applicants should possess a Ph.D. degree in Immunology/Cell Biology/Biochemistry, or a related field in Biological Sciences with peer-reviewed publication(s). Those with a background in immunology or biochemistry are particularly encouraged to apply. Experience with molecular and cell biology, Western blot/immunoprecipitation methods is essential. Experience in working with mouse models is a plus. Competitive candidates are expected to have excellent oral and written communication skills, to be organized, and to work easily with others in the laboratory as a team player.

To apply: Interested applicants should send their CV and a list of three references to Shanjana-Awasthi@ouhsc.edu by e-mail.

Shanjana Awasthi, Ph.D., Assistant Professor, Department of Pharmaceutical Sciences, Adjunct Assistant Professor, Department of Microbiology and Immunology, Associate member, Peggy and Charles Stephenson Cancer Center, University of Oklahoma Health Science Center, College of Pharmacy, Room No. 324, 1110 N. Stonewall Avenue, Oklahoma City, OK-73117; Ph: 405-271-6593 (X47332); e-mail: Shanjana-Awasthi@ouhsc.edu; Fax: 405-271-7505.

University of Oklahoma Health Sciences Center

Postdoctoral position cellular and molecular biology and biochemistry at USA

A postdoctoral position is available in the Division of Nephrology, Department of Medicine at Massachusetts General Hospital and Harvard Medical School. The main focus of the lab is to study interplay of extracellular matrix-integrin signaling and trafficking of membrane transporters (mainly water channels and vasopressin receptor V2R) and epithelial polarity complex, how “epithelial features” is established/remodeled during kidney development and after tubular injury, and understand the epithelial repairing process mediated by tubular “progenitor” cells. We are applying comprehensive approaches and model systems including real time imaging, 3D culture, organ culture, transgenic mouse and zebrafish models for the study. We are looking for highly motivated and devoted candidates with PhD and/or MD degrees and solid training in cellular and molecular biology and biochemistry. Individuals with research experience in protein trafficking, epithelial cell biology and/or kidney development/physiology are particularly welcome to apply. Please send a CV and contact information to:

Dr. H. Jenny Lu, MD, PhD

Assistant Professor in Medicine 


Division of Nephrology


Department of Medicine


Massachusetts General Hospital and Harvard Medical School

CPZN 8150
185 Cambridge St, Boston, MA 02114


Email: halu@partners.org

Postdoc position at Center for Cell and Gene Therapy at BCM, United States

A postdoc position is available now in the Center for Cell and Gene Therapy at BCM. The highly motivated postdoc will be involved in translational studies of cancer immunotherapy. The project is going to evaluate new combinational therapy of genetic modified human T cells from patients and vaccination in mice model for the future application in clinical trails at Baylor. All applicants with experience in molecular biology, human immunology, cancer research, and mouse models are encouraged to apply.

This position will provide the opportunity to apply cutting-edge immunological techniques in immune cells . This position will also serve as an ideal step to advance the potential candidate’s career in academia or industry. Trainees will have access to the resources of the Center for Cell and Gene Therapy at Texas Children’s Hospital.  Please contact by email to xsong1@bcm.edu<mailto:xsong1@bcm.edu>.

To apply

Interested candidates with experience on vaccinia virus are encouraged to send their curriculum vitae and contact information of references to: Xiao-Tong Song, Ph.D. at xsong1@bcm.edu

Postdoc position in cell biology Albert Einstein College of Medicine in New York

A POSTDOCTORAL FELLOWSHIP is available in Pamela Stanley’s lab at the Albert Einstein College of Medicine in New York to identify specific roles for glycans during spermatogenesis. The Stanley lab has shown that complex N-glycans are essential for spermatogenesis, and also identified a novel inhibitor of complex N-glycan synthesis that is proposed to regulate spermatogenesis. Mutant mice have been developed to identify specific roles for N-glycans and the functions of the novel inhibitor during spermatogenesis. Publications are linked to the laboratory homepage at: http://stanxterm.aecom.yu.edu/

Recent PhD graduates are strongly preferred. Applicants should have extensive expertise in molecular and cell biology, developmental biology, and using mouse genetic models. First author publication(s) in peer-reviewed, English language journals are necessary. Candidates with outstanding credentials may be eligible for a Harry Eagle Fellowship http://www.einstein.yu.edu/departments/cell-biology/harry-eagle-scholar/ Ability to work independently, creativity, motivation and a strong work ethic are important. A curriculum vitae with a description of research experiences and contact information for three references should be sent togianette.fata@einstein.yu.edu Subject: Stanley Spermatogenesis Application

The Department of Cell Biology has a strong core of postdoctoral fellows and graduate students, working in diverse areas of development, cell biology, immunology and cancer biology. The Department is highly interactive, meets weekly for work-in-progress seminars, and biweekly for a journal club and hosts numerous outside seminar speakers. http://www.einstein.yu.edu/departments/cell-biology/

The Albert Einstein College of Medicine (Einstein) is one of the nation’s premier institutions for basic research and clinical investigation with 300+ research laboratories funded by more than $200 million from the National Institutes of Health. There are ~350 PhD students, including 125 in the combined MD/PhD programs, and ~350 postdoctoral fellows at Einstein. http://einsteinpostdocs.info/  

Albert Einstein College of Medicine of Yeshiva University is an Equal Opportunity Employer.

To apply

Applicants should send a curriculum vitae and a description of research interests and experience, with the contact information of three references to gianette.fata@einstein.yu.edu. Subject:Stanley Spermatogenesis Application

Postdoctoral Position in Cell Biology and Biochemistry, 2013

We are looking to hire a motivated, independent and enthusiastic individual who will conduct research projects related to the biochemistry of vessel growth. The selected candidate will work in the brand new Wolfe Labs Research Center and be affiliated with the departments of Biochemistry and/or Ophthalmology of the University of Montreal.

Requirements:

The candidate will be expected to perform and/or supervise biochemical analysis, rodent surgeries and experiments pertaining to cell physiology. Prior experience with basic cell and molecular biology, animal work and microscopy and are an asset. A PhD in Biochemistry, Cell Biology, Neuroscience or Physiology or related field is required. Applicants should provide by email a CV, list of 3 references as well as a brief cover letter stating prior research experience and general scientific interests.

Research Focus:

Angiogenesis (the generation of new blood vessels from pre-existing ones) is a highly synchronized process requiring the coordinated efforts of several vascular and non-vascular cell populations and a stringent orchestration by the tissue being vascularized. Stereotyped angiogenesis is vital for both developmental growth and to restore tissue oxygenation and metabolic supply following vascular injury.

Given that angiogenesis becomes deregulated in numerous pathological contexts such as cancer and ischemic neuropathies, it is key to understand the molecular and cellular mechanism that ensure sound vessel growth. Our laboratory studies angiogenesis with a focus on ocular vascular systems. We tackle these diseases by studying vascular growth and the factors that regulate it. Moreover, we are interested in the cellular interactions and intracellular mechanisms that govern vessel growth in both physiological and pathological contexts.

For More Information

Postdoctoral position to study Epithelial Cell Biology 2013 USA

Postdoctoral position available for a fellow with an interest in Epithelial Cell Biology (New York University School of Medicine).

The laboratory is studying the cell biology of the urinary bladder urothelium. The research focuses on the molecular mechanisms of the synthesis and subcellular trafficking of uroplakins. It is supported by an NIH Program Project grant that includes a team of five investigators (Michael Rindler, PhD and Gert Kreibich, membrane biogenesis; Tung-Tien Sun, PhD, urothelial biology and stem cells; Xiangpeng Kong, PhD, atomic structure of membrane proteins; and Xue-Ru Wu, MD, urinary tract infection). Thus the group offers excellent exposure to multiple disciplines and collaborative opportunities that have led to the discovery that uroplakins play a key role in urothelial barrier function, the establishment of mouse transgenic and gene knockout models for studying uroplakin traffic, and the demonstration that uroplakins are the major receptors for uropathogenic E. coli causing urinary tract infection.

Please send a cover letter, CV and contact information for three references to michael.rindler@nyumc.org

Michael Rindler, Ph.D.
Associate Professor
Department of Cell Biology
New York University School of Medicine
Alexandria Center for Life Sciences
450 East 29th St, Room 826
New York, NY 10016
Tel: 212-263-5812
FAX: 212-263-5100

NYU is an equal opportunity employer

Postdoctoral Research position at Cancer Center and Research Institute USA

A Postdoctoral Research position is immediately available in the laboratory of Dr. Jin Q. Cheng at the H. Lee Moffitt Cancer Center and Research Institute. This is an entry-level position for an individual with less than 2 years post-graduate experience in which the individual will be responsible for conducting independent research projects. We are seeking a highly motivated individual to investigate signal transduction pathways and non-coding RNA in human malignancy which could lead to targeted therapies. Candidates should have a Ph.D. degree in Biochemistry/Molecular Biology or a related field. Expertise in cancer signaling, cell cycle and mouse model is highly desirable.

Moffitt Cancer Center is a modern facility on the University of South Florida Campus that conducts research on various aspects of Cancer Biology with emphasis on translational research. The Research environment includes state of the art modern core facilities and pathogen-free modern animal facilities, access to clinical material, etc.

Please apply to position 10943 at www.moffitt.org/careers, and email your CV, a brief summary of research experience and career goals, and contact information for three professional/academic references to jin.cheng@moffitt.org.
 
H. Lee Moffitt Cancer Center & Research Institute is an equal opportunity, affirmative action employer, and a drug free workplace

Postdoctoral Position to study Programmed DNA Elimination 2013 USA

Postdoctoral position available to study PROGRAMMED DNA ELIMINATION in NEMATODES (Chromatin Diminution). In the nematode Ascaris, 15% of the genome is eliminated in the somatic lineages during the 3rd through 5th cleavage (4 to 16 cell stage), while the germline genome remains intact. ~700 germline and early development expressed genes are eliminated. Chromosomes break, regions are lost, and new and increased numbers of chromosomes are formed. Areas under investigation include analysis of 1) how genome regions are marked for retention or elimination, 2) how break regions are identified and the mechanism of chromosome breaks, 3) how eliminated chromosome regions are selectively lost from holocentric chromosomes, and 4) the contributions of histone modifications (including CenpA) and non-coding RNAs to DNA elimination. For a recent paper, see Developmental Cell 2012. 23:1072–1080.
For additional information on the laboratory's research and recent publications, see http://140.226.65.22/Davis_lab/index.html
The University of Colorado School of Medicine, is located in a brand-new, state-of-the-art facility on the Anschutz Medical Campus. The Department of Biochemistry and Molecular Genetics provides an exciting, interactive and collegial scientific environment.

Denver, CO is an affordable multicultural, metropolitan city. The nearby Rocky Mountains offer a spectacular scenic backdrop and an array of outdoor recreational opportunities within a 15-minute to two-hour drive from Denver. The climate in Denver is relatively mild and dry, and Denver boasts over 300 days of sunshine per year! Winters are mild, with average daytime highs of 45 degrees; summers are warm and dry, with average daytime highs of 85 degrees.

Applicant must have PhD degree in Biological Sciences, Chemistry, Biochemistry, Molecular Biology, Genetics, Cell Biology, or a related field within the last three years. Applicant must have excellent communication skills using the English language. Applicants should have demonstrated scholarship through publication in internationally recognized English language journals.

Candidate is expected to be curious, highly motivated and able to design and carry out creative, independent research, write fellowship applications (if applicable), and publish.

Applicants should have significant experience in at least one or more of the following:
1. Epigenetics, chromatin, DNA damage/repair, or genomics
2. Mitosis, centromeres, or chromosome segregation
3. ChiP and ChiP-seq
4. Genomics and Bioinformatics
5. Non-coding RNAs and chromatin
6. Immunocytochemistry of nuclei and chromosomes including DNA and/or RNA FISH
7. Laser ablation and microinjection
8. C. elegans

Applications will be reviewed until suitable candidates are identified.
Applicants should apply by e-mail to richard.davis@ucdenver.edu
Applications should contain:
1. A letter of application including a short description of previous research experience, goals, and interests in our research
2. Curriculum Vitae
3. Contact information for three references
4. Start date availability

Full contact information:
Richard E. Davis, Ph.D.
Dept. of Biochemistry and Molecular Genetics
University of Colorado School of Medicine
RC-1 South, RM 10121, MS 8101
12801 East 17th Ave
Aurora, CO 80045
Tel: 303-724-3226
Fax: 303-724-3215

 Application Deadline:     Open Until Filled

Ion Channel Research Postdoctoral Fellowship 2013 United States

A postdoctoral position is available in the laboratory of Dr. Yongchang Chang of the Barrow Neurological Institute, St. Joseph's Hospital and Medical Center. Post-doctoral fellow will work on projects to study structure and function of ligand-gated ion channels (mainly GABA_A/C receptors) using molecular biological, electrophysiological, fluorescent, and computational techniques.

Highly motivated individuals with a Ph.D. in Physiology, Biophysics, Neuroscience, Molecular Pharmacology, and other related biological fields are encouraged to apply. Relevant experience (molecular biology, voltage-clamp, kinetic modeling, homology modeling, etc.) and strong motivation and interest are desirable. 

To apply

Please send your CV, statement of research interest, and names/addresses of three referees to Dr. Yongchang Chang at yongchang.chang@dignityhealth.org

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