The laboratory is studying the cell biology of the urinary bladder urothelium. The research focuses on the molecular mechanisms of the synthesis and subcellular trafficking of uroplakins. It is supported by an NIH Program Project grant that includes a team of five investigators (Michael Rindler, PhD and Gert Kreibich, membrane biogenesis; Tung-Tien Sun, PhD, urothelial biology and stem cells; Xiangpeng Kong, PhD, atomic structure of membrane proteins; and Xue-Ru Wu, MD, urinary tract infection). Thus the group offers excellent exposure to multiple disciplines and collaborative opportunities that have led to the discovery that uroplakins play a key role in urothelial barrier function, the establishment of mouse transgenic and gene knockout models for studying uroplakin traffic, and the demonstration that uroplakins are the major receptors for uropathogenic E. coli causing urinary tract infection.
Please send a cover letter, CV and contact information for three references to michael.rindler@nyumc.org
Michael Rindler, Ph.D.
Associate Professor
Department of Cell Biology
New York University School of Medicine
Alexandria Center for Life Sciences
450 East 29th St, Room 826
New York, NY 10016
Tel: 212-263-5812
FAX: 212-263-5100
NYU is an equal opportunity employer