Cell/ developmental biology/ Biophysics - Postdoctoral position 2013 at Denmark

The Novo Nordisk Foundation Section for Basic Stem Cell Biology (BasicStem) at DanStem and the Faculty of Health and Medical Sciences, University of Copenhagen, has been established to promote basic and applied research on stem cell- and developmental biology of medical relevance. The Center comprises a wide range of expertise and skills, from embryological model systems, mouse genetics, stem cell studies, and in vitro culture systems to stem cell therapeutics. Currently, we have recruited >40 staff members to our research groups and staff functions, and expect to expand to around 60 scientists in the future.
Job Description:

We are recruiting an outstanding, ambitious postdoctoral candidate with a strong background in interdisciplinary cell/developmental biology and biophysics to join our group. The postdoctoral candidate will study how mechanotransduction via cell-cell interactions and cytoskeletal dynamics controls pancreatic morphogenesis and cell fate specification. The primary focus in this project will be to develop and analyse novel time lapse imaging models for simultaneous tracking of changes in cell shape, migration, polarity and fate. Towards this goal a combination of unique fluorescent reporter mouse strains will be inter-crossed with various mouse models with conditional gene inactivation of key morphogenetic regulators (including Rho GTPases and downstream components) in the developing mouse pancreatic epithelium. The candidate should have previous experience with confocal microscopy on an advanced level, and ideally also experience with live imaging of cells/organs using fluorescent reporters. Furthermore, experience in mouse genetics, fine dissection, Imaris and/or Fiji software, and script writing is considered of particular relevance.
Qualifications:

•     A PhD in cell biology, genetics, developmental biology, biophysics or a similar field;
•     An excellent publication record along with experience in developmental biology/biophysics is essential;
•     Advanced training and experience (>3 years) in confocal microscopy is essential;
•     Experience in live imaging as well as 3D and movie processing in Imaris/Fiji or similar software is ideal;
•     Experience with the mouse as an experimental model and mouse genetics is ideal;
•     Strong motivation and excellent scientific skills are essential;
•     Good English communication skills, both oral and written;
•     An analytical aptitude of devising innovative scientific or technical solutions;
•     Demonstrate enthusiasm, motivation, flexibility and confidence.

Application Instruction

The application must be submitted in English, by clicking on?
The closing date for applications is 23.59pm, 30th April 2013.

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