Based at Pirbright, you will be employed on a recently funded BBSRC sLOLA project (The Molecular Biology of FMDV Replication: Towards New Methods of FMDV Disease Control). In collaboration with top UK universities (St Andrews, Dundee, Edinburgh and Leeds), we will use FMDV sequence analysis, codon-pair bias analysis, siRNA screens, and state-ofthe-art quantitative proteomics (including SILAC) to improve our understanding of FMDV replication with the specific target of identifying host-factors that influence the outcome of infection (acute and persistent infections). This information will be used to improve the effectiveness and safety of FMDV vaccines.
Reporting directly to the Head of Molecular Characterisation and Diagnostics Group, the post holder will undertake sequencing studies to understand the extent of natural sequence variability for FMD virus and undertake systematic studies to test the importance of specific genomic features using reserve genetics and siRNA approaches.
ORGANISATION POSITION
The post will report to the Head of Molecular Characterisation and Diagnostics Group. It will be based in the LVD programme.
MAIN DUTIES AND RESPONSIBILITIES
Responsible will include:
You will work full time on the project described above.
This job description is only an outline of the tasks, responsibilities and outcomes required of the role. The jobholder will carry out any other duties as may be reasonably required by his/her line manager. The job description and personal specification may be reviewed on an Page 2 of 3 ongoing basis in accordance with the changing needs of the Human Resources Division and The Pirbright Institute.
All employees shall actively participate in the Institute- wide quality assurance system in conjunction with the Institute’s Quality Manager. Employees are also expected to safeguard their own health and safety and security by following policies and all employees are responsible for the Health and Safety and security of staff under their management.
PERSON SPECIFICATION (QUALIFICATION AND EXPERIENCE)
Qualifications and Experience
Essential:
- A PhD in a Biological Science subject or an equivalent qualification;
- For non-UK nationals IELTS qualification overall mark of 7.0 (with no lower than 7.0 for listening and reading, no lower than 6.5 for speaking and no lower than 6.0 for writing);
- Experience of Virology;
- Knowledge of modern molecular biology techniques relevant to this project;
- Good publication record consistent with experience.
Desirable:
- Experience of mammalian cell biology;
- Experience of reverse genetics.
- Specific skills
Essential:
- Must be bright and self-motivated;
- Evidence of good communication skills, including the ability to communicate effectively;
- Be out-going, a good team player and likely to interact well with colleagues;
- Evidence of wanting to lean and improve.