Thursday, April 11, 2013

Cancer Research UK-funded Postdoc position to study DNA damage signalling 2013

Cancer Research UK-funded Postdoctoral Research Fellow position is immediately available in the laboratory of Professor Laurence Pearl FRS and Dr Antony Oliver, to study the structural basis for the assembly and specificity of multi-protein complexes involved in the recognition and repair of DNA damage, and DNA damage signalling.
The internationally renowned MRC Genome Damage and Stability Centre and the School of Life Sciences are very well equipped for all aspects of modern structural biology, with state-of-the-art laboratories for molecular biology, recombinant expression in bacterial and eukaryotic hosts, biochemistry, biophysics and X-ray crystallography.
Excellent synchrotron access (~ 2 days/month) is also available through rolling beam-allocation programmes at both the Diamond Light Source and ESRF.
Applicants must have a PhD, and extensive experience in recombinant expression and protein purification. Previous experience of crystallization and X-ray crystallography would be a distinct advantage.
The post-holder will be responsible for expression, purification, crystallization and structure determination of protein-protein and protein-DNA complexes, plus downstream biochemical and biophysical characterisation.

http://www.sussex.ac.uk/aboutus/jobs/090