A post-doctoral position is available for Innovative projects that focus on innate immune mechanisms triggering adaptive immune responses in lupus. The projects include: novel pathways that regulate macrophages (cutaneous and kidney), identifying aberrant macrophages linked to lupus, and determining the unique and shared role of the principle macrophage developmental molecules in immune mediated inflammation. Unique transgenic strains and knockout mice with reporter genes have been constructed on lupus-susceptible strains for these projects. These projects in mice have human translational components in patients with cutaneous lupus and lupus nephritis (biomarkers, therapeutic targets).
Required Experience:
Immunology and Molecular/Cell Biology
In vivo mouse systems
Computer literacy
In vivo mouse systems
Computer literacy
Desired:
Experience with macrophages
Responsible, hard-working individual who is able to multi-task and to work independently
Responsible, hard-working individual who is able to multi-task and to work independently
M.D. or Ph.D. required.
To apply: Please send CV and three references. Interested candidates contact:
Vicki Rubin Kelley, Harvard Institutes of Medicine, 4 Blackfan Street, Boston, MA 02115; FAX 617-525-5830; e-mail:vkelley@rics.bwh.harvard.edu.