A postdoctoral position is available at the University of Michigan Geriatric Center to study molecular genetics of aging and age-related functional decline using the nematode C. elegans as model organism.
Our current research is focused on the following three major themes: (1) The role of heat-shock transcription factor (HSF) in longevity regulation (Hsu et al. Science, 300: 1142-5; Chiang et al, Cell, 148: 322-4). (2) The role of sirtuins in stress response and aging (Chiang et al, PLoS Genetics, 8: e1002948). (3) Genes involved in the longevity response to dietary restriction (Ching et al, Aging Cell, 9: 545-57). Experiments will involve classical molecular and cellular biology techniques, genetic manipulations in C. elegans and biochemical assays.
Candidates should be highly motivated and comfortable with using multiple techniques to solve complex problems. A M.D. or Ph.D. degree in genetics, cell biology, molecular biology, biochemistry or related fields is required. Experience in genetics or worm biology is highly preferred.
Interested individuals should email a cover letter, her/his CV, and the contact information of 3 references to: aolinhsu@umich.edu.