Germany Postdoc position in Immunology

We are looking for a Postdoc (m/f) in Immunology
 
The candidate will join the newly established Stroke-Immunology Group at the Institute
for Stroke and Dementia Research of the Ludwig-Maximilians-University in Munich
(www.isd-muc.de). We are interested in the interactions between the immune system
and the brain after acute brain injury with a particular focus on how sterile brain injuries
modulate the systemic immune response. Using a broad panel of cutting edge methods
in immunology and neuroscience we aim to detect the pathophysiological mediators of
immunomodulation after acute brain injury and the long-term effects on remote organ
function.

We offer a Postdoctoral scientist position in an international and dynamic atmosphere with
access to state of the art laboratory facilities. As part of the excellence cluster “Munich Cluster
for Systems Neurology (SyNergy)” (www.synergy-munich.de) and active collaborator on the
large biomedical campus in Munich we provide a highly collaborative research environment.

We are looking for a highly motivated postdoctoral fellow with experience in immunology and cell biology. Advanced knowledge in flow cytometry, cell culture and cell biology as well as excellent communication skills in English are a prerequisite. Additional experience in neuroimmunology or neuroscience is favourable but not necessary.

Salary is according to TV-L. The position is limited for two years, with a possible extension.

Disabled persons will be preferentially considered in case of equal qualifications. Presentation costs can not be refunded.

Please send a cover letter outlining your research interest and work experience, a CV,
two letters of recommendation and key publications as one pdf file to Dr. Arthur Liesz at Arthur.Liesz@med.uni-muenchen.de.
(Please use the Job-Number: 2013-K-0128 for your application.)

Germany: Post-doctoral position for Biostatistician / Statistician

The Center for Innovation Competence (ZIK), Department of Host Septomics under the direction of Prof. Dr. Hortense Slevogt is offering a post-doctoral position as (bio-) statistician starting as soon as possible.
 

Post-doctoral position: Biostatistician / Statistician

The position is fixed for 2,5 years in the first instance.

Profile
We are seeking a statistician to investigate molecular patterns of sepsis infections.

The role will require the statistical analysis of large-scale genomic, proteomic and transcriptomic datasets. The position is an excellent opportunity for those with experience in biostatistics, or individuals with a strong quantitative background who are interested in working in an exciting interdisciplinary research area between biology, medicine and statistics.
The key responsibilities of the role include the statistical evaluation of proteomics data obtained from mass spectrometry, and prospectively next-generation sequencing. Additionally, the successful candidate will support the “Host Septomics” researchers with high-quality statistical input into all research activity.

You will have a postgraduate qualification (Ph.D./ M.Sc.) in (bio-) statistics or equivalent with a strong quantitative component. In addition, you have experience in working with large data sets and have applied statistical methodologies, preferably in biology or medicine. You will need to be proficient in the use of statistical software, ideally R, and should have excellent computing and communication skills. Knowledge of gene expression analysis and omics data is not required. Rather we are seeking candidates who enjoy applying statistics to explore current biomedical issues.

About ZIK Host Septomics
Host Septomics examines, analyzes and characterizes these host responses during the course of sepsis. The fundamental understanding of this complex interaction enables innovative diagnostic approaches and therapeutic methods to fight sepsis.

Host Septomics works with methods of functional genomics and proteomics from patients to pathogens as well as using state-of-the-art molecular and cell biology techniques. With this methodology, comparative analyses of transcriptomic and proteomic patterns from healthy and infected tissue are possible. This step is essential in discovering new, important proteins and biomarkers in the course of sepsis. The identified “targets” will be analyzed in view of their diagnostic and therapeutic suitability by using samples obtained from animal models, septic patients and subsequent clinical studies.

The hiring will be made according to prevailing legal norms for limited employment contracts. Severely disabled people with same aptitude will be given preference.

How to apply: 
We recommend to use no folder and to hand in copies only, because your application form will be destroyed according to data protection rules after the hiring process is finished.

Thus it is more favourable to use the possibility of an online application at http://www.uniklinikum-jena.de/MedWeb/-p-13174.html?offerId=1087.

Postdoctoral Position - Next Generation Biotechnology 2013 Germany

KIT - Karlsruhe Institute of Technology Karlsruhe, Germany


Starting Date: from 1st November 2013 on

Duration: 18 months

Funding: German Federal Ministry of Education and Research (Program: "Next Generation Biotechnology - Biotechnologie 2020+")

In the frame of the transdisciplinary project "Biomolecular Interaction Engineering" funded by the German Federal Ministry of Education and Research, the newly created group of Dr Guillaume Delaittre is seeking a highly motivated postdoctoral researcher to engineer proteins, particularly enzymes, in order to incorporate them into biohybrid nanostructured materials. Molecular biology protocols as well as direct chemical modifications are envisaged in order to stabilize the biomolecules and equip them with a wider range of surface chemical functionality, while maintaining their biological activity.
Interaction with a broad range of biologists, chemists, physicists, and engineers will be facilitated by the physical and scientific embedding of the research team at the transdisciplinary Institute of Toxicology and Genetics. Collaboration with the internationally renowned Polymer and Materials Chemistry team of Prof. Barner-Kowollik will be promoted through our joint weekly group seminar. Importantly, the KIT is a multidisciplinary research institute offering access to nearly all scientific equipment one can think of.
The applicants must have completed a PhD degree in Biology (or Chemistry). Prior hands-on experience with protein modification is a strict requirement. A successful candidate is mandatorily well-versed in modern protein biochemistry and characterization, e.g., gel electrophoresis, mass spectrometry, liquid (affinity or size-exclusion) chromatographies, UV and fluorescence spectroscopies, enzyme and antibody assays, light scattering. Ideal applicants also possess knowledge in enzyme kinetics. Although it is not a strict requirement, applicants who are familiar (at least theoretically) with analytical methods such as NMR, electron microscopy, and surface characterization techniques and have a background in organic and polymer chemistry will be in a good position. Some interest in materials-related research is welcome. A good level of English is essential.

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Proteomics: Senior Postdoctoral researcher position Germany 2013

Description The neuroproteomics laboratory (Prof. Stefan Lichtenthaler) seeks a senior postdoc with extensive experience in LC-MS/MS. We offer excellent projects and training in neurodegeneration and protease research. Specifically, the lab uses proteomic, biochemical and molecular biological techniques to study
the molecular mechanisms underlying neurodegenerative diseases (e.g. Alzheimer’s disease) and
proteases, which regulate the communication between cells in the brain (regulated intramembrane proteolysis).

We are an international and interdisciplinary team, are part of several larger research consortia (e.g. DFG-funded excellence cluster SyNergy) and are associated with the Technical University Munich.

Responsibilities You will use quantitative proteomics to study the role of proteases and other proteins in neurodegeneration and related fields. You will also use our novel proteomic SPECS method and will develop new proteomic methods to study neurodegeneration. This position offers the possibility for “Habilitation”. In addition, you will lead the proteomics part of the neuroproteomics lab. This includes supervision of the proteomic experiments of two PhD students and of support personnel. You supervise proteomic analyses for collaborative projects and organize the maintenance of the two mass spectrometers (LTQ Orbitrap Velos/Q Exactive) in the group.

Qualifications and experience You have a PhD, extensive experience in proteomics and in nanoLC-MS/MS and are familiar with Orbitrap mass spectrometers, documented by publications. We expect detailed knowledge in statistics and data processing with relevance to mass spectrometry. You are creative, highly motivated and you are able to work independently. Essential qualities include good organizational skills, fluency in English, a strong team spirit and time management skills. Appointment is full time and will be initially for two years with the possibility of renewal.

We offer an interesting and challenging position in a research institute focused on relevant topics of neurodegenerative disease research in an academic and international environment.
The infrastructure of the center in Munich offers diverse opportunities for personal development of the employees; human resource development is an important concern in our Institute.
Employment, payment and social benefits are determined by the Public Sector Collective Agreement (Tarifvertrag für den öffentlichen Dienst – TVöD). The job location is München, Germany. The DZNE is an equal opportunity employer. The DZNE especially welcomes and encourages disabled individuals to apply.

Send application to:  Applications including motivation letter, CV, publication list (if applicable) and two recommendation letters or references (in a single PDF-File) should be sent via e-mail to: carolin.nierwetberg@dzne.de

Last date to apply : 31. July 2013

Postdoctoral position cell signalling 2013, Germany

A PhD position and a postdoctoral position are available in project 1 (Feil) of the newly established DFG Research Unit FOR 2060. Project start is summer 2013. The Research Unit investigates the function of the intracellular signalling molecule, cyclic guanosine monophosphate (cGMP) in mammals, specifically in tissue degeneration and regeneration. Project 1 studies the role of global and local cGMP signals in growth control. We use fluorescence-based cGMP sensor proteins to visualize changes of the signalling molecule in living cells in real time. This will allow us to monitor the spatiotemporal dynamics of cGMP signalling under various conditions and to correlate the respective cGMP signals with associated alterations in the growth of cardiovascular and neuronal cells. The projects involve analyses at the molecular, cellular and whole organism level. Candidates should be interested to work at the interface of biochemistry and biomedicine, with a focus on cell signalling under native conditions. Experience in the fields of signal transduction, transgenic mouse technology, and/or live cell imaging would be an advantage.

For recent project-relevant publications of our group, see:
Original Article: Thunemann, Wen et al. (2013). Transgenic mice for cGMP imaging. Circ Res, in press.
Methods Article: Thunemann et al. (2013). Visualization of cGMP with cGi biosensors. Methods Mol Biol 1020, 89-120.
Review Article: Kemp-Harper & Feil (2008). Meeting report: cGMP matters. Sci Signal 1, pe12.

For further information, please visit www.cyclic-gmp.de or www.ifib.uni-tuebingen.de/forschung/feil.html.

Please send your application (including names/emails of 2 referees) to Prof. Dr. Robert Feil, University of Tübingen, Interfakultäres Insitut für Biochemie (robert.feil@uni-tuebingen.de).

Deadline for applications: 16 August 2013

Postdoctoral fellow position in Immunology/ Cell / Molecular Biology/ Biochemistry at Germany

The research group „Inflammatory signalling in alloimmunity and infection“
at the 3rd Medical Deparmtment of Hematology and Oncology (Director: Univ.-Prof. Dr. Christian Peschel) at Klinikum rechts der Isar (Technische Universität München) is offering a position for a

Postdoctoral fellow
Our research group studies the interplay between innate and adaptive immunity in infectious
and malignant diseases and is situated in a highly stimulating research environment. Our
research is supported by the German research foundation and the Else-Kröner-Research-Foundation.

Applicants should have a MD or PhD or equivalent doctoral degree with at least 3 years of
proven research experience in Immunology, Cell / Molecular Biology or Biochemistry. Prior
experience with in vivo technologies will be of advantage. The ideal candidate should be a
highly motivated and goal-oriented researcher, provide a good publication record, be able to
work in a team as well as show some experience in the supervision of graduate students or
master students.
Payment is according to tarif (TV-L). We give priority to severely disabled applicants with essentially equal qualifications.

Please submit your complete application documents (including CV, motivation letter,
publication list and references - all documents within a single PDF file) via E-mail to:

PD Dr. med. Hendrik Poeck or Dr. med. Tobias Haas
III. Medizinische Klinik und Poliklinik
Klinikum rechts der Isar
der Technischen Universität München
Ismaninger Straße 22 ∙ 81675 München

Email: hendrik.poeck@lrz.tum.de or tobias.haas@lrz.tu-muenchen.de
Website:
http://www.med3.med.tu-muenchen.de/forschung/Grundlagenforschung/Tumorimmunologie/haaspoeck.html

Postdoc position Microbiology/ Biochemistry 2013, Germany

Research of structure, function, biosynthesis and host interaction of bacterial cell envelope components word wide has attracted more and more interest in the recent years. Members of the SFB 766 have contributed to this development: The SFB 766 has already generated a strong international reputation in it`s first 4 year funding period.

In the second funding period we have one open positions for two years for a

PhD student or postdoc (E13, 65%) with the topic

"The bacterial cell envelope as a target structure for dermcidin"

PhD students or postdocs will work on a challenging project at the frontier of the current research. The research group is located at the University Hospital, Department of Dermatology.

The candidate should have a completed diploma / master degree in Microbiology, Biochemistry or related disciplines and a strong background and interest in genetic,biochemical or biophysical methods and microbiological procedures.

The University of Tübinges strives to increase the percentage of female researchers and is explicitly urging scientifically qualified women to apply. Disabled scientists with equal qualification will be hired preferentially.

Please send your full application to:
Prof. Dr. rer. nat. Birgit Schittek, University of Tübingen, Department of Dermatology, Lieberemeisterstr. 25, 72076 Tübingen or per email to birgit.schittek@med.uni-tuebingen.de
Application deadline: July 31th, 2013

For further information please contact Prof. Dr. Birgit Schittek (see email adress above).

Postdoc position organic chemistry Germany 2013

Postdoc (m/f)

Code-No.: 2013/B 12
The place of employment is Teltow (Berlin, Germany).

The Helmholtz-Zentrum Geesthacht in Geesthacht, near Hamburg, and in Teltow, near Berlin, conducts materials and coastal research. You can find more information at www.hzg.de.

The Institute of Biomaterial Science in Teltow of the Helmholtz-Zentrum Geesthacht invites applications for a Postdoc (m/f) in Material Sciences, focussing on polyester- and polydepsipeptide-based matrices, their synthesis and exploration of in vitro and in vivo degradation mechanisms. This is initially a 2-years fixed-term contract.

You will be strengthening our research activities in the analysis of the in vivo behaviour of polymeric biomaterials in an interdisciplinary and interinstitutional research network. You will be responsible for the synthesis of polyester-/depsipeptide-based multiblock copolymers. You will study polymer morphology, polymer architecture including polymer sequence structure of polymer systems as prepared, during degradation in vitro, and as explants from in vivo studies (GPC, mass spectrometry, NMR, etc.) as well as degradation products. In addition you will explore the applicability of a robotic synthesis platform for the synthesis of these polymer systems and will take care about the biological evaluation of the materials. You will be responsible for the benchwork of your own projects and will furthermore actively participate in the publication of the results and preparation of patent applications.

You have a PhD in organic chemistry, polymer chemistry, or material science with practical experience in the synthesis of monomers and their polymerization. Applicants with a strong interest in translational research are especially welcome. You will work in an interdisciplinary team with chemists, material engineers, biologists, pharmaceutical scientists, immunologists, and scientists of other disciplines in the field of regenerative medicine. You are speaking English fluently and can provide documentation of your completed studies and possibly additional or international project work.

Informal enquiries can be directed to marc.behl@hzg.de.

We offer an appropriate salary related to TV-AVH as well as the usual public sector social benefits. The advancement of equality at the Helmholtz-Zentrum Geesthacht goes without saying; in particular, we are striving to increase the percentage of women in the science sector. Severely disabled persons with equal qualifications will be considered preferentially within the framework of legal requirements.

Please send your application indicating job offer code-no. 2013/B 12 including your CV, description of your scientific expertise, publication list, copies of credentials (B.Sc., M.Sc., PhD) including grades, and names and addresses of three academic referees preferably by e-mail to personal.teltow@hzg.de or to Helmholtz-Zentrum Geesthacht, Institut für Biomaterialforschung, Kantstraße 55, 14513 Teltow, Germany. For details of the institute, please visit the website at http://biomaterials.hzg.de.

Closing date for applications is July 29th 2013.

Postdoctoral researcher position in Computational Systems Biology, Gemany

One postdoctoral researcher position (3+2 years) and one PhD student position (3 years) are available in theComputational Systems Biology group at Jacobs University Bremen for a project: 

Re-classification of chronic inflammatory diseases using network signatures derived from high-throughput data

Project Outline:
The evidence that network architecture determines aspects of biological function, both on the levels of gene regulation and metabolism, is incontrovertible. Furthermore, a wide range of abstract model studies has demonstrated that network architecture shapes dynamical processes.
Here we will analyze and interpret the diverse high-throughput data available for various aspects of chronic inflammatory disorders by contextualizing them within given biological networks.
Data will be provided by our collaborators on the clinical side (the Cluster of Excellence “Inflammation at Interfaces” in Kiel). 
The network methods established and applied here offer the possibility of identifying coherent patterns in transcriptome data and other high-throughput data sets. Put together with predictions of metabolic fluxes and with network- and flux-based microbiome modeling, these approaches will serve as a foundation for better classifying and interpreting patient subgroups, disease progressions and treatment responses.

For further information on the topic, see: 
Sonnenschein, N., Golib Dzib, J.F., Lesne, A., Boulkroun, S., Zennaro, M.-C., Benecke, A. and Hütt, M.-Th. (2012) A network perspective on metabolic inconsistency. BMC Systems Biology 6, 41.
Beber, M., Fretter, C., Jain, S., Sonnenschein, N., Müller-Hannemann, M. and Hütt, M.-Th. (2012) Artifacts in statistical analyses of network motifs: General framework and application to metabolic networks. Roy. Soc. Interface 7, 3426-3435.
Sonnenschein, N., Geertz, M., Muskhelishvili, G. and Hütt, M.-Th. (2011) Analog regulation of metabolic demand. BMC Systems Biology 5, 40.
Marr, C., Theis, F.J., Liebovitch, L.S. and Hütt, M.-Th. (2010) Patterns of subnet usage in the transcriptional regulatory network of Escherichia coli. PLoS Computational Biology 6, e1000836.


Candidates should have a background or strong interest in Computational Systems Biology, Bioinformatics or Statistical Physics of Complex Networks and solid programming skills (e.g., Matlab/Mathematica/C++/Python).


How to apply: 
Interested candidates are encouraged to submit a CV, contact details of two references and a short statement of research interest electronically to:

m.huett@jacobs-university.de


To be assured of full consideration, applications must arrive by August 18, 2013

Germany: Postdoctoral Scientist position in Bioinformatics/ Computational Biology/ Plant Genomics

The Max Planck Institute for Molecular Genetics is an international research institute with approximately
350 employees. A special focus lies on genome analysis of man and other organisms.

The Department “Vertebrate Genomics”, group “Comparative and Functional Genomics” (Head: Dr. Heinz Himmelbauer), invites applications for the following open position:

Postdoctoral Scientist (f/m)

Bioinformatics/Computational Biology/Plant Genomics

(TVöD E13)

Code: 13-12 L

Responsibilities:
The AnnoBeet project is funded by the German Ministry for Education and Research with the goal to analyse the genome sequence of the crop plant sugar beet (Beta vulgaris) with respect to structural variation and gene functions. The successful candidate will pursue projects related to genomic sequencing data. She/He will adapt existing tools or implement new software to assemble high-fidelity genome sequences from wild-derived and domesticated beets. Data are mainly from the Illumina sequencing platform but also from other technologies which enable the generation of long reads. Assembled genomes will be compared to related genomes to extract and interpret biologically relevant differences.

Qualifications:
We are looking for a scientist (PhD in bioinformatics or related field) with solid programming skills (ideally experience in developing sequence analysis tools), experience in handling (large) sequencing data sets, knowledge of molecular genetics and understanding of lab methods and also knowledge of genome sequencing concepts. Experience in analysis of Illumina sequencing data is an advantage.  

The group has successfully performed several projects using 454- and Illumina technologies. We recently completed a reference sequence for the sugar beet genome (http://bvseq.molgen.mpg.de). We are a multidisciplinary team and offer work in a lively and friendly atmosphere and state-of-the art computing infrastructure. We are looking forward to expanding our team by a dedicated and strongly motivated person with distinct interest in the challenges of modern sequencing technologies.

The position is initially available for one year. The working place will be at the Center for Genomic Regulation (http://www.crg.es) in Barcelona/Spain. It is located at the seafront close to the Olympic harbor and combines excellent science with an inspiring environment in the heart of Barcelona with its cultural attractions, beach and metropolitan flair. The employment contract will be concluded with the Max Planck Institute for Molecular Genetics in Berlin/Germany. The salary will be according to the German collective agreement for the public service (TVöD), depending on academic level and previous experience.

The  Max  Planck  Society  is  committed  to  employing  more  handicapped  individuals  and  especially encourages them to apply. The Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.

Send application to: 
For informal inquiries by e-mail, please contact Dr. Heinz Himmelbauer (himmelbauer@molgen.mpg.de). Applications including summary of Master's and PhD theses, publication list, and contact details for three references should be sent by August 16, 2013 via e-mail to:
 
job-1312@molgen.mpg.de

PostDoc position in Glycomics and Glycoproteomics at Germany

Within the 5(+3) years BMBF 2020+ project: „Forschertandem zum Aufbau einer Plattform zur in-vitro N-Glykosylierung von (therapeutischen) Proteinen unter Ausnutzung einer Kaskade isolierter Enzyme“, the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg (Germany) offers the position of aPostDoc on the topic of:

 

„Glycomics and Glycoproteomics“
Keyword: PD-glyx-062013JV

In the Bio/Process Analytic team of the Bioprocess Engineering Group a new PostDoc position is available. The position is intended to start as soon as possible and you will work 39 hours per week.
 

Topic and position
Glycosylation is an important modification of proteins, and is involved in the regulation of the biological activity and stability of many proteins. Notably, the glycosylation of many eukaryotic proteins appears to be highly regulated and minor structural changes of the glycan portions may lead to major changes in function. Therefore, protein glycosylation analysis is becoming increasingly important in medical/clinical, biopharmaceutical, as well as biotechnological research.
You will be part of the institute’s Bioprocess Engineering department. The research project is assigned to the Bio/Process-Analytics group, which is headed by Dr.rer.nat. Erdmann Rapp. As a postdoc at the Max Planck Institute you will join a multidisciplinary team working on the deeper understanding of bio(techno)logical processes on the molecular level developing and using proteomic, glycoproteomic and glycomic tools. Within the BMBF project on “synthetic biology” you will develop and improve cutting edge methods for analysis of protein glycosylation. With a particular focus on in vitro synthesis of glycans, you will apply these methods for studying protein glycosylation, unraveling the protein glycosylation process with respect to its understanding and optimization.
 
Institute
The Max Planck Institute for Dynamics of Complex Technical Systems is the first institute of the Max Planck Society dedicated to the engineering sciences and is supposed to bridge the gap between basic research and industrial applications. The neighborhood to the Otto-von-Guericke University and its engineering and medical faculties offers excellent cooperation possibilities. The main research activities are focused on the analysis and synthesis, the design and control of processes in chemical and bio-engineering. Scientists of different disciplines like engineering, chemistry, biology, mathematics and computer sciences add their specific knowledge to the research work, thereby developing new methods and tools for tackling problems in other application areas.
 
Your profile
We are looking for outstanding young international and German scientists. You hold a recent PhD in analytical chemistry, biochemistry or biomedical sciences. You hold an excellent university degree of - or equivalent to - a Master or Diploma degree from a German university. You have substantial practical experience with bio-analytical techniques such as HPLC, CE and mass spectrometry with respect to glycomics/glycoproteomics and experience in glycobiology. Very good communication skills in both written and spoken English are essential as is the motivation, the interest and the ability to integrate and work into our interdisciplinary team.
 
We offer

• Cutting edge laboratories and instrumentation
• Collaboration in a friendly, international und interdisciplinary team.
• Positive and motivating working atmosphere.

We offer a TVöD E 13 position according to the German public pay scale. The Max Planck Society is an equal opportunity employer. The goal is to enhance the percentage of women where they are underrepresented. Women, therefore, are especially encouraged to apply. The Society is committed to employing more handicapped people. Applications of handicapped persons are particularly welcome.
 
More information
If you have any questions regarding the research project please contact Dr. Erdmann Rapp (email: rapp@mpi-magdeburg.mpg.de).
 
Apply
If you are interested in this position and you satisfy the requirements of the profile, we encourage you to apply. Please send an e-mail including complete application documents, a document describing your reasons to apply, and the names of three possible referees to Annegret Frauendienst (email: sek-bpe@mpi-magdeburg.mpg.de, phone: +49 391 6110-200).

Postdoctoral position in tumor biology, Germany

The Institute of Experimental Internal Medicine offers a Postdoctoral position (E13, TV-L)(m/f).

Applicants who have a commitment to scientific excellence as documented by a strong publication record are especially encouraged to apply.

The research program of the institute encompasses scientific projects on the regulation of the NF-kappaB system in the pathophysiology of infection, inflammation and tumor biology (e.g. differentiation and cell cycle control). Here, the molecular and cell biological mechanisms of the intracellular signal transmission are of special interest. The institute allows an internationally competitive research by providing state of the art technologies in protein analysis, mass spectrometry and microscopy.

The institute cooperates with the clinics of the Centre of Internal Medicine in teaching and research and coordinates or participates in a variety of coordinated programs funded by the German Research Foundation (GRK1167, SPP1365, SFB779, SFB854), the Federal Ministry of Education and Research (SysTec) and the European Union (Marie Curie Research Training Network). Further, the institute is member of the interdisciplinaryResearch Center Dynamic Systems: Biosystems Engineering funded by the Federal State of Saxony-Anhalt within the Excellence Program.

The Otto von Guericke University wishes to increase the proportion of female academic personnel. Women are therefore explicitly encouraged to apply. Handicapped persons with equivalent qualification will be given preference.

Please send your application together with the usual documents (CV, list of publications, present and past extramural funding etc.) to: Prof. M. Naumann (naumann@med.ovgu.de). For further information please visit our webpage: http://www.med.uni-magdeburg.de/ieim.html.

Send application to: 
naumann@med.ovgu.de

Prof. Dr. M. Naumann
Institute of Experimental Internal Medicine
Medical Fakulty Otto von Guericke University
Leipziger Str. 44
D-39120 Magdeburg

PostDoc Position in computational systems biology at Germany

We are looking for enthusiastic candidates for postdoctoral positions in reverse engineering as well as applying and developing methods for the analysis and integration of heterogeneous high-throughput data. These are required and to be applied to a portfolio of international research projects. The candidates will be involved in reverse engineering of regulatory networks of the corresponding target systems; and analysis and integration of large experimental datasets obtained from project collaborators using appropriate computational platform. These positions require extensive communication and collaboration with computational modelers, bioinformaticians, biologists, microbiologists, engineers, and clinicians.
 
Requirements
For these positions we request a solid background in computational biology and a good understanding of molecular biology. In addition, you are characterized by a high degree of independence and responsibility. Dedication, teamwork and persuasiveness complete your profile. Due to our international orientation, good knowledge of English is essential.
 
In particular:

• Knowledge in pattern recognition, machine learning, multivariate statistics and large-scale data mining;
• Experience in inference of the underlying regulatory networks of prokaryotes, yeast, algae, and/or mammalian cells using transcriptomics and proteomics data;
• Good programming skills (e.g. C, C++, Python, Perl, Matlab or equivalent) and experience with data integration platform development;
• Ability to collaborate independently with other project members to implement, develop, and refine relevant computational tools;
• Experience in doing research in a multi-disciplinary team;
• High interest in biological challenges and in combining different scientific disciplines to develop new insights and skills;
• Willingness to learn new skills to support other computational tasks when necessary;
• Willingness to travel to our European partners is prerequisite. Depending on your qualification a 2-4 week stay in the Netherlands may be required during the familiarization phase.  

 
Qualifications

• PhD degree in Computational Life Science, Bioinformatics, Physics or an equivalent discipline;
• Practical experience dealing with gene ontology, annotations notions, and public repositories of omics data;
• Extensive experience in C, C++, Python, Perl, or equivalent plus ability to work with other programming languages;
• Fluency in written and spoken English.

 
We offer 2 post-doc positions with an average working time of 40 hours per week for each position for a period of 2 years with possibility of extension. The payment will correspond to the fare of the public service depending on your qualification.

Please apply electronically with your CV, cover letter, and supporting information in a single document (max. 3MB). The application deadline is July10th, 2013.

info@lifeglimmer.com

Postdoc positions in the field of Cancer Biology, Germany

The Institute of Neuropathology at the Justus Liebig University in Giessen, Germany, Director Prof. Till Acker, is inviting applications for
 

2 Postdoc positions:
The microenvironmental control of tumor progression and metastasis

The positions are available immediately.
 
Your profile:
We are looking for enthusiastic and highly motivated applicants holding, or about to obtain, a PhD degree. The applicants should possess a strong research background in molecular and cell biology, experience in cancer research will be an advantage. Preference will be given to applicants with previous experience in one or more of the following areas: protein biochemistry, analysis of signalling pathways, proteomic analysis including analysis of posttranslational modifications, hypoxic signalling, functional genomics or other high-throughput screening methods, epigenetics or in vivo tumor metastasis models.
 
Topic:
Our group has a long-standing interest in the role of microenvironmental factors, particularly hypoxia, hypoxia inducible factors (HIFs) and oxygen sensors of the PHD family, in the regulation of tumor progression and key hallmarks of cancer including angiogenesis, invasion, metastasis, metabolism and differentiation. Our main research interest is to understand the role of microenvironmental sensors and their downstream targets in tumor progression and metastasis.
The proposed projects will aim to dissect the intersection of oxygen sensing pathways with other cellular signalling pathways, including growth factor/RTK and Notch signalling, which are involved in cancer cell proliferation, invasion, metastasis and self-renewal.
 
What we offer:
Our international team offers an open, supportive, dynamic and motivating academic environment with excellent training opportunities. We have won a number of external research grants and are involved in several national and international collaborative projects. We use a wide spectrum of methods: cloning, cell culture, biochemistry, qRT-PCR, FACS, ELISA, cell-based assays (proliferation, apoptosis, migration, 3D invasion, stem cell isolation and cultivation etc.), shRNA screens, proteomics, transactivation assays, virally-based gene delivery and RNAi silencing, immunohistochemistry, in situ hybridization, light, epifluorescence and confocal microscopy, image analysis, animal models and in vivo tumor models.
 
Application:
Please send your applications, including a CV, certificates and references to Dr. Boyan Garvalov
Email: Boyan.Garvalov {at} patho.med.uni-giessen.de;
Please cite reference “Jobvector2013-06”.
 
Website: http://www.ukgm.de/ugm_2/deu/ugi_npa/5424.html
 
Selected references:
Filatova et al, Biochim Biophys Acta 2013, 1830(2):2496-508
Sawamiphak et al, Nature 2010; 465(7297):487-91
Henze et al, Cancer Research 2010;70(1):357-66
Seidel et al, Brain 2010;133(4):983-95
Acker et al, Cancer Cell 2005; 8(2):131-41
Compernolle et al, Nature Medicine 2002; 8(7):702-10

Biochemistry Postdoctoral position at Germany

The University of Lübeck is a modern Life-Science University with seven academic programs including Medicine, Informatics, Medical Informatics, Molecular Life Science, Infection Biology, Mathematics in Medicine and Life Science and Medical Engineering.

Within the medical section, the Institute for Systemic Inflammation Research (ISEF), (Director: Prof. Dr. med. Jörg Köhl), invites the application from a highly motivated candidate for a:
 

Postdoctoral position

The initial appointment will be for 2 years starting September 1, 2013. Continued employment following the fixed term is possible.

The laboratory focuses on the role of the complement system in acute and chronic inflammatory diseases of the lung, the skin and the gastrointestinal tract. Inflammatory bowel disease is often associated with the activation of the complement system and the generation of the anaphylatoxins (AT) C3a and C5a. In different experimental models, we have shown that ATs function not only as mediators but also as important regulators of systemic inflammation (e.g. Mucosal Immunol. 2013 6:807; Nat. Med. 2012 18:1401). This project aims at delineating the molecular mechanisms underlying AT-driven regulation of mucosal tolerance and induction of inflammatory bowel disease. The project is funded by the German Research Foundation (DFG).

Position requirements include a doctoral degree (Dr. rer. nat. / PhD) in biology, biochemistry or equivalent. A prerequisite for the position is experience in mouse models of inflammation. Preference will be given to candidates experienced in isolation and purification of immune cells (from the intestine) and their phenotypic characterization by flow cytometry. Due to the strong international ties of the laboratory (www.irtg1911.uni-luebeck.de), solid command of the English language is essential.

The position will be paid according to the regulations of the civil service collective wage agreement (TV-L13 100%). Applications of women are strongly encouraged. Handicapped candidates with equivalent qualifications will be given preference.

Please submit your application including informative documents (motivation letter, CV, list of publications and 2 references) by July 12, 2013 to:

Prof. Dr. Jörg Köhl
Institute for Systemic Inflammation Research
University of Lübeck
Ratzeburger Allee 160
23538 Lübeck, Germany
Email: bewerbung@isef-luebeck.de
http://www.isef.uni-luebeck.de
Phone: +49-451-500-3308

Biochemist Postdoctoral Fellow United States

Under the general direction of the principal investigator, plan and carry out experiments designed to identify and characterize pathways and processes in sulfate reducing bacteria (SRB) which are targeted by environmentally relevant stresses. Specific attention will be focused on understanding the range of factors responsible for iron sulfur cluster cofactor biosynthesis and repair in SRBs.

SPECIFIC RESPONSIBILITIES:

• Characterize strains of Desulfovibrio vulgaris Hildenborough which possess null mutations in predicted FeS cluster biosynthesis components using biochemical assays for FeS enzyme activities and phenotypic screens.
• Perform chemogenomic fitness profiling of D. vulgaris mutants, using appropriate stress conditions, and contribute to the development of genetic interaction screening techniques which utilize a next generation sequencing based assay.
• Identify and characterize additional genes associated with FeS cluster biosynthesis and other systems linked to energy generation and metal homeostasis using chemogeneomic and genetic interaction fitness profiling techniques. Communicate with informatics analysis and data management colleagues to ensure correct and efficient data integration and interpretation.
• Use advanced spectroscopic approaches (CD, EPR) to characterize proteins of interest where required.  
• Provide research support and assistance to other members of the laboratory as requested.
• Keep detailed records of experimental procedures and results and communicate data to group and PI via individual and group meetings.

To apply

For full consideration, follow the link below to job posting and apply directly to Berkeley Lab.  As part of the online application process, please complete a profile, including uploading attachments relevant to the opportunity. 

https://lbl.taleo.net/careersection/2/jobdetail.ftl?lang=en&job=76019

Berkeley Lab is an affirmative action/equal opportunity employer committed to the development of a diverse workforce.

Postdoctoral Position in Systems Biology 2013 Germany

The Institute of Molecular Biology (IMB) is an Excellence Centre for Life Science, funded by the Boehringer Ingelheim Foundation, and located within the campus of the Johannes Gutenberg University, Mainz, Germany. Applications are invited for Postdoc positions in the research group “Modeling of Biological Networks” . Our group applies mathematical modeling to understand cell-to-cell variability and the dynamics of gene regulatory networks.

You will:

• Develop mechanistic mathematical models of intracellular regulatory networks
• Work in close collaboration with Dr. Legewie and other group members
• Be willing to collaborate with internal and external partners

Required qualifications:

• PhD in biology, physics, mathematics or a related discipline
• Background in biology and nonlinear dynamics
• One first author paper in an international peer reviewed journal
• Good written and spoken English

We offer:

• An interesting, diverse and international working environment

• Competitive salary
• Favourable pension scheme
• Advanced Training opportunities
• Flexible working hours

How To apply:

please submit an electronic application, which should include a cover letter, your CV (in English), a letter of application, contact address of a professional referee and certificates of your degrees topersonnel@imb-mainz.de quoting reference (#SLPD03).

Informal enquires should be addressed to Dr Stefan Legewie (s.legewie@imb-mainz.de). IMB is an equal opportunity employer.

Starting date: 1 September 2013 Duration: Initially 2 years; option of further extension.

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